Ciliated hepatic foregut cyst: a case report and review of literature on a rare hepatic cystic lesion.
| Title: | Ciliated hepatic foregut cyst: a case report and review of literature on a rare hepatic cystic lesion. |
|---|---|
| Authors: | AlQattan AS; Department of Surgery, King Fahad Specialist Hospital, Dammam, Saudi Arabia.; AlSharit MA; Department of Surgery, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.; AlQatari AA; Department of Surgery, King Fahad Hospital of the University, Khobar, Saudi Arabia.; Binkhamis L; Department of Surgery, King Fahad Hospital of the University, Khobar, Saudi Arabia.; Al Zaharani H; Department of Radiology, King Fahad Specialist Hospital, Dammam, Saudi Arabia.; Mansi N; Department of Surgery, King Fahad Specialist Hospital, Dammam, Saudi Arabia. |
| Source: | Annals of medicine and surgery (2012) [Ann Med Surg (Lond)] 2025 Oct 30; Vol. 87 (12), pp. 8953-8958. Date of Electronic Publication: 2025 Oct 30 (Print Publication: 2025). |
| Publication Type: | Case Reports; Journal Article |
| Language: | English |
| Journal Info: | Publisher: Wolters Kluwer Country of Publication: England NLM ID: 101616869 Publication Model: eCollection Cited Medium: Print ISSN: 2049-0801 (Print) Linking ISSN: 20490801 NLM ISO Abbreviation: Ann Med Surg (Lond) Subsets: PubMed not MEDLINE |
| Imprint Name(s): | Publication: 2023- : [London] : Wolters Kluwer; Original Publication: London : Surgical Associates Ltd., 2012- |
| Abstract: | Introduction: Ciliated hepatic foregut cyst (CHFC) is one of the rarely reported cystic lesions of the liver, with approximately 200 cases reported in the literature. Although most patients with CHFC are asymptomatic and diagnosed incidentally, they should be investigated thoroughly to rule out other possible differential diagnoses, as CHFCs carry a risk of malignant transformation into squamous carcinoma.; Case Presentation: A 19-year-old female was found to have a liver lesion during laparoscopic appendectomy for acute appendicitis. Post-appendectomy liver imaging revealed a solitary 6.4 cm well-defined, multilocular cystic lesion centered in the left liver without features of malignancy. There was no communication with the biliary system; however, there was mild dilatation of the intrahepatic biliary radicles. The differential diagnoses included biliary cystadenoma, simple cyst, and cystic biliary hamartoma. Based on these findings and the absence of malignant features in the cyst, an open cholecystectomy and nonanatomical resection of segments 4/5 was performed. The patient had an uneventful postoperative recovery and was discharged in good condition. Histopathological examination revealed a CHFC, and the patient was followed up for 2 years without complications.; Discussion: CHFC is a rare benign liver cyst with the potential for malignant transformation. Among 223 reported cases, 2.7% were malignant. Most lesions are found incidentally, typically in segment IV. Owing to the variable imaging features, a definitive diagnosis requires histological confirmation. Larger cysts or those with irregular walls pose a higher risk. Surgical excision, preferably laparoscopic, is the treatment of choice, with no reported recurrences. The role of surveillance for small, asymptomatic cysts remains controversial.; Conclusion: Accurate preoperative diagnosis of CHFC is often challenging. Nevertheless, given its potential for malignant transformation, a high index of suspicion is warranted in such cases. When clinical and radiological features raise concerns, complete surgical excision remains the treatment of choice.; (Copyright © 2025 The Author(s). Published by Wolters Kluwer Health, Inc.) |
| Competing Interests: | The authors declared that no conflict of interest. |
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| Contributed Indexing: | Keywords: ciliated hepatic foregut cyst; liver; liver resection; squamous cell carcinoma |
| Entry Date(s): | Date Created: 20251211 Date Completed: 20251211 Latest Revision: 20251223 |
| Update Code: | 20260130 |
| PubMed Central ID: | PMC12689037 |
| DOI: | 10.1097/MS9.0000000000004098 |
| PMID: | 41377347 |
| Database: | MEDLINE |
Case Reports; Journal Article