Helicobacter pylori eradication rate following first line non-bismuth quadruple therapy regimen in Tunisian patients: the HPERAD study.
| Title: | Helicobacter pylori eradication rate following first line non-bismuth quadruple therapy regimen in Tunisian patients: the HPERAD study. |
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| Authors: | Fekih M; Department of Gastroenterology, A La Rabta Hospital, Tunis, Tunisia.; Jomni T; Department of Gastroenterology, Internal Security Forces Hospital La Marsa, Tunis, 2070, Tunisia.; Ayari M; Department of Gastroenterology, Internal Security Forces Hospital La Marsa, Tunis, 2070, Tunisia. ayari.myriam@hotmail.fr.; Battikh H; Department of Microbiology, La Rabta Hospital, Tunis, Tunisia.; Zribi M; Department of Microbiology, La Rabta Hospital, Tunis, Tunisia.; Labidi A; Department of Gastroenterology, A La Rabta Hospital, Tunis, Tunisia.; Serghini M; Department of Gastroenterology, A La Rabta Hospital, Tunis, Tunisia.; Ben Zid N; Department of Gastroenterology, A La Rabta Hospital, Tunis, Tunisia.; Hafi M; Department of Gastroenterology, A La Rabta Hospital, Tunis, Tunisia.; Boubaker J; Department of Gastroenterology, A La Rabta Hospital, Tunis, Tunisia.; Nciri A; Department of Gastroenterology, Fattouma Bourguiba Hospital, Monastir, Tunisia.; Ben Abdelwahed M; Department of Gastroenterology, Fattouma Bourguiba Hospital, Monastir, Tunisia.; Zakhama M; Department of Gastroenterology, Fattouma Bourguiba Hospital, Monastir, Tunisia.; Loghmari MH; Department of Gastroenterology, Fattouma Bourguiba Hospital, Monastir, Tunisia.; Baklouti R; Department of Gastroenterology, Fattouma Bourguiba Hospital, Monastir, Tunisia.; Guediche A; Department of Gastroenterology, Fattouma Bourguiba Hospital, Monastir, Tunisia.; Bouhlel W; Department of Gastroenterology, Fattouma Bourguiba Hospital, Monastir, Tunisia.; Jemni I; Department of Gastroenterology, Fattouma Bourguiba Hospital, Monastir, Tunisia.; Sabbek A; Department of Gastroenterology, Fattouma Bourguiba Hospital, Monastir, Tunisia.; Chaabene NB; Department of Gastroenterology, Fattouma Bourguiba Hospital, Monastir, Tunisia.; Safer L; Department of Gastroenterology, Fattouma Bourguiba Hospital, Monastir, Tunisia.; Haddad O; Microbiology Laboratory, Fattouma Bourguiba University Hospital, Monastir, Tunisia.; Kadri Y; Microbiology Laboratory, Fattouma Bourguiba University Hospital, Monastir, Tunisia.; Rhim H; Microbiology Laboratory, Fattouma Bourguiba University Hospital, Monastir, Tunisia.; Mastouri M; Microbiology Laboratory, Fattouma Bourguiba University Hospital, Monastir, Tunisia.; Belhadj Mabrouk E; Department of Gastroenterology, Charles Nicolle Hospital, Tunis, Tunisia.; Mensi A; Department of Gastroenterology, Charles Nicolle Hospital, Tunis, Tunisia.; Ayadi S; Department of Gastroenterology, Charles Nicolle Hospital, Tunis, Tunisia.; Zaimi Y; Department of Gastroenterology, Charles Nicolle Hospital, Tunis, Tunisia.; Said Y; Department of Gastroenterology, Charles Nicolle Hospital, Tunis, Tunisia.; Mouelhi L; Department of Gastroenterology, Charles Nicolle Hospital, Tunis, Tunisia.; Debbeche R; Department of Gastroenterology, Charles Nicolle Hospital, Tunis, Tunisia.; Kchaou M; Department of Gastroenterology, Avicenne Clinic, Tunis, Tunisia.; Haddad W; Department of Gastroenterology, Avicenne Clinic, Tunis, Tunisia.; Chtourou L; Department of Gastroenterology, Hédi Chaker Hospital, Sfax, Tunisia.; Chabchoub H; Department of Gastroenterology, Ibn Nafis Clinic, Sfax, Tunisia.; Turki M; Department of Gastroenterology, Ibn Nafis Clinic, Sfax, Tunisia.; Njeh M; Department of Gastroenterology, Ibn Nafis Clinic, Sfax, Tunisia.; Mzid A; Department of Gastroenterology, Ibn Nafis Clinic, Sfax, Tunisia.; Medjahed N; Department of Gastroenterology, Ibn Nafis Clinic, Sfax, Tunisia.; Mnif B; Department of Microbiology, Hédi Chaker Hospital, Sfax, Tunisia.; Hammami A; Department of Microbiology, Hédi Chaker Hospital, Sfax, Tunisia.; Abdallah HB; Department of Gastroenterology, Principal Military Hospital of Instruction of Tunis, Tunis, Tunisia.; Mohamed G; Department of Gastroenterology, Principal Military Hospital of Instruction of Tunis, Tunis, Tunisia.; Abdelli N; Department of Gastroenterology, Principal Military Hospital of Instruction of Tunis, Tunis, Tunisia.; Abdelaali I; Department of Gastroenterology, Internal Security Forces Hospital La Marsa, Tunis, 2070, Tunisia.; Douggui MH; Department of Gastroenterology, Internal Security Forces Hospital La Marsa, Tunis, 2070, Tunisia.; Medhioub M; Department of Gastroenterology, Mohamed Taher El Maamouri Hospital, Nabeul, Tunisia.; Khsiba A; Department of Gastroenterology, Mohamed Taher El Maamouri Hospital, Nabeul, Tunisia.; Mahmoudi M; Department of Gastroenterology, Mohamed Taher El Maamouri Hospital, Nabeul, Tunisia.; Mohamed AB; Department of Gastroenterology, Mohamed Taher El Maamouri Hospital, Nabeul, Tunisia.; Yakoubi M; Department of Gastroenterology, Mohamed Taher El Maamouri Hospital, Nabeul, Tunisia.; Hamzaoui L; Department of Gastroenterology, Mohamed Taher El Maamouri Hospital, Nabeul, Tunisia.; Azzouz MM; Department of Gastroenterology, Mohamed Taher El Maamouri Hospital, Nabeul, Tunisia.; Bibani N; Department of Gastroenterology, Habib Thameur Hospital, Tunis, Tunisia.; Trad D; Department of Gastroenterology, Habib Thameur Hospital, Tunis, Tunisia.; Sabbah M; Department of Gastroenterology, Habib Thameur Hospital, Tunis, Tunisia.; Jlassi H; Department of Gastroenterology, Habib Thameur Hospital, Tunis, Tunisia.; Elloumi H; Department of Gastroenterology, Habib Thameur Hospital, Tunis, Tunisia.; Gargouri D; Department of Gastroenterology, Habib Thameur Hospital, Tunis, Tunisia.; Bouchabou B; Department of Gastroenterology, Mongi Slim Hospital, Tunis, Tunisia.; Nakhli A; Department of Gastroenterology, Mongi Slim Hospital, Tunis, Tunisia.; Hemdani N; Department of Gastroenterology, Mongi Slim Hospital, Tunis, Tunisia.; Ennaifer R; Department of Gastroenterology, Mongi Slim Hospital, Tunis, Tunisia.; Bel Hadj Ammar L; Department of Gastroenterology, Mahmoud El Matri Hospital, Ariana, Tunisia.; Nsibi S; Department of Gastroenterology, Mahmoud El Matri Hospital, Ariana, Tunisia.; Tlili R; Department of Gastroenterology, Mahmoud El Matri Hospital, Ariana, Tunisia.; Kallel L; Department of Gastroenterology, Mahmoud El Matri Hospital, Ariana, Tunisia.; Hamida SB; Department of Gastroenterology, Habib Bougatfa Hospital, Bizerte, Tunisia.; Elloumi H; Department of Gastroenterology, Habib Bougatfa Hospital, Bizerte, Tunisia.; Cheikh I; Department of Gastroenterology, Habib Bougatfa Hospital, Bizerte, Tunisia.; Nouira M; Preventive Medicine Department, Faculty of Medicine of Tunis, Tunis, Tunisia.; Ennigrou S; Preventive Medicine Department, Faculty of Medicine of Tunis, Tunis, Tunisia. |
| Source: | BMC infectious diseases [BMC Infect Dis] 2025 Dec 25; Vol. 26 (1), pp. 197. Date of Electronic Publication: 2025 Dec 25. |
| Publication Type: | Journal Article |
| Language: | English |
| Journal Info: | Publisher: BioMed Central Country of Publication: England NLM ID: 100968551 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2334 (Electronic) Linking ISSN: 14712334 NLM ISO Abbreviation: BMC Infect Dis Subsets: MEDLINE; In Process |
| Imprint Name(s): | Original Publication: London : BioMed Central, [2001- |
| Competing Interests: | Declarations. Ethical approval: The study was carried out in accordance with the current version of the Helsinki Declaration (52 nd WMA General Assembly, Edinburgh, Scotland, October 2000) and the guidelines of the International Conference on Harmonization (ICH) on Good Clinical Practice (GCP). The study protocol was approved by the Ethical committee of La Rabta Hospital. Reference ethics approval number: CEBM.EPS.HR/PRN 75/2020. All patients provided written informed consent to participate in the study before being included. Consent for publication: All the authors have agreed to submit the manuscript for publication. Competing interests: The authors declare no competing interests. |
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| Contributed Indexing: | Keywords: Helicobacter pylori; Concomitant quadruple therapy; Eradication; First-line treatment; Multicenter; Non-bismuth therapy; Prospective study |
| Entry Date(s): | Date Created: 20251225 Latest Revision: 20260131 |
| Update Code: | 20260131 |
| PubMed Central ID: | PMC12849162 |
| DOI: | 10.1186/s12879-025-12405-0 |
| PMID: | 41449381 |
| Database: | MEDLINE |
Journal Article