Pediatric Intracerebral Hemorrhage Management-Consensus Statement of the International Pediatric Stroke Organization-Part 1: Acute Phase and Workup.
| Title: | Pediatric Intracerebral Hemorrhage Management-Consensus Statement of the International Pediatric Stroke Organization-Part 1: Acute Phase and Workup. |
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| Authors: | Boulouis G; Diagnostic and Interventional Neuroradiology CIC-IT 1415, CHRU de Tours, INSERM 1253 iBrain Tours Centre Val de Loire France.; French National Reference Center for Pediatric Stroke Paris France.; Fox CK; Departments of Neurology and Pediatrics University of California San Francisco San Francisco CA USA.; Waak M; Queensland Children's Hospital Paediatric Intensive Care Unit South Brisbane Queensland Australia.; Sporns PB; Department of Neuroradiology University Hospital Basel Basel Switzerland.; Mailo JA; Division of Pediatric Neurology, Department of Pediatrics University of Alberta Edmonton Alberta Canada.; Beslow LA; Division of Neurology, Children's Hospital of Philadelphia, Departments of Neurology and Pediatrics Perelman School of Medicine at the University of Pennsylvania Philadelphia PA USA.; Wintermark M; Department of Neuroradiology MD Anderson Houston TX USA.; Chung MG; Department of Pediatrics, Divisions of Pediatric Neurology and Critical Care Medicine Nationwide Children's Hospital Columbus OH USA.; Harrar DB; Department of Neurology Children's National Hospital Washington DC USA.; Vossough A; Department of Radiology Children's Hospital of Philadelphia Philadelphia PA USA.; Hausman-Kedem M; Pediatric Neurology Institute, Dana-Dwek Children's Hospital, Tel Aviv Medical Center Tel Aviv Israel.; Faculty of Medicine Tel Aviv University Tel Aviv Israel.; Naggara O; French National Reference Center for Pediatric Stroke Paris France.; GHU Paris Psychiatrie et Neurosciences, CH Sainte-Anne, Inserm Université de Paris Cité, Institut de psychiatrie et neurosciences de Paris, Service d'imagerie morphologique et fonctionnelle, UMRS1266 Paris France.; Jiang B; Department of Radiology, Neuroradiology Section Stanford University Stanford CA USA.; Requejo F; Department of Neuroradiology JP Garrahan National Pediatric Hospital Buenos Aires Argentina.; Chaudhary N; Department of Radiology University of Michigan Ann Arbor MI USA.; Benichi S; Department of Pediatric Neurosurgery, Assistance Publique-Hôpitaux de Paris Necker-Enfants Malades Hospital, Université Paris Cité Paris France.; Radvany MG; Radiology in the Department of Clinical Sciences Nova Southeastern University Dr. Kiran C Patel College of Allopathic Medicine Davie FL USA.; Martinez M; Edward Singleton Department of Radiology Texas Children's Hospital Austin TX USA.; Vadivelu S; Department of Neurosurgery Cincinnati Children's Hospital Medical Center Cincinnati OH USA.; Kansagra AP; Department of Neurointerventional Surgery California Center for Neurointerventional Surgery San Diego CA USA.; Aagaard-Kienitz B; Department of Neurological Surgery University of Wisconsin School of Medicine and Public Health Madison WI USA.; Martí-Fàbregas J; Stroke Unit Department of Neurology Hospital de la Santa Creu i Sant Pau Barcelona Barcelona Spain.; Chikkannaiah M; Department of Neurology Dayton Children's Hospital Dayton OH USA.; Wright State University Boonshoft School of Medicine Dayton OH USA.; Pasi M; Stroke Unit, Neurology Department CIC-IT 1415, CHRU de Tours, INSERM 1253 iBrain Tours Centre Val de Loire France.; Grossberg JA; Department of Neurosurgery Emory University Hospital Atlanta GA USA.; Chevignard M; Rehabilitation Department for Children with Acquired Neurological Injury Saint Maurice Hospitals, Saint Maurice. Sorbonne Université, INSERM, CNRS, Laboratoire d'Imagerie Biomédicale, LIB Paris France.; Mrakotsky C; Departments of Neurology & Psychiatry Boston Children's Hospital, Harvard Medical School Boston MA USA.; Fullerton HJ; Departments of Neurology and Pediatrics University of California San Francisco San Francisco CA USA.; Dlamini N; Division of Neurology The Hospital for Sick Children Toronto Ontario Canada.; Lehman LL; Department of Neurology Boston Children's Hospital Boston MA USA.; Harvard Medical School Boston MA USA. |
| Source: | Journal of the American Heart Association [J Am Heart Assoc] 2026 Jan 06; Vol. 15 (1), pp. e039594. Date of Electronic Publication: 2025 Dec 30. |
| Publication Type: | Consensus Statement; Journal Article; Practice Guideline |
| Language: | English |
| Journal Info: | Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101580524 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2047-9980 (Electronic) Linking ISSN: 20479980 NLM ISO Abbreviation: J Am Heart Assoc Subsets: MEDLINE |
| Imprint Name(s): | Original Publication: Oxford : Wiley-Blackwell |
| MeSH Terms: | Cerebral Hemorrhage*/therapy ; Cerebral Hemorrhage*/diagnosis ; Stroke*/therapy ; Stroke*/diagnosis; Adolescent ; Child ; Child, Preschool ; Humans ; Infant ; Infant, Newborn ; Consensus ; Delphi Technique |
| Abstract: | Pediatric intracerebral hemorrhage (pICH) is a rare but serious neurologic emergency associated with significant morbidity. Although pICH accounts for nearly half of all pediatric strokes, it remains understudied, and dedicated evidence-based management guidelines are lacking. To address this gap, the International Pediatric Stroke Organization convened a multidisciplinary international working group in 2020 to develop a comprehensive, consensus-based framework for the acute evaluation and management of pICH in children aged 28 days to 18 years. The working group included child neurologists, neurointensivists, neurosurgeons, neuroradiologists, and neurointerventionalists. Subgroups conducted systematic literature reviews and formulated key clinical questions. A modified Delphi process was used to derive consensus statements across 6 domains: prehospital and emergency care, diagnostic imaging and workup, neurocritical care and medical management, neurosurgical and neurointerventional approaches, and identification of knowledge gaps. Through rounds of structured review and voting, 21 consensus statements were developed and approved. The process was endorsed by multiple professional societies. This represents the first international, multidisciplinary, multisociety consensus statement focused on the acute management of pICH in children. It provides structured, expert-driven guidance to inform clinical decision-making, reduce practice variability, and highlight areas for future research. These consensus statements aim to support clinicians worldwide in improving outcomes for children with pICH. |
| Comments: | Comment in: J Am Heart Assoc. 2026 Jan 6;15(1):e045930. doi: 10.1161/JAHA.125.045930.. (PMID: 41467397) |
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| Contributed Indexing: | Keywords: nontraumatic cerebral hemorrhage; pediatric hemorrhagic stroke; pediatric intracerebral hemorrhage |
| Entry Date(s): | Date Created: 20251230 Date Completed: 20260108 Latest Revision: 20260218 |
| Update Code: | 20260218 |
| PubMed Central ID: | PMC12909056 |
| DOI: | 10.1161/JAHA.124.039594 |
| PMID: | 41467366 |
| Database: | MEDLINE |
Consensus Statement; Journal Article; Practice Guideline