Mpox in endemic regions in Nigeria: awareness, knowledge, and willingness to accept the mpox vaccine.
| Title: | Mpox in endemic regions in Nigeria: awareness, knowledge, and willingness to accept the mpox vaccine. |
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| Authors: | Olufadewa II; Centre for One Health and Zoonotic Diseases, Slum and Rural Health Initiative, Ibadan, Nigeria.; Adesina MA; Centre for One Health and Zoonotic Diseases, Slum and Rural Health Initiative, Ibadan, Nigeria.; Oladele RI; Centre for One Health and Zoonotic Diseases, Slum and Rural Health Initiative, Ibadan, Nigeria.; Olufadewa TA; Centre for One Health and Zoonotic Diseases, Slum and Rural Health Initiative, Ibadan, Nigeria.; Okpokoro E; International Research Centre of Excellence, Institute of Human Virology, Nigeria, Abuja, Nigeria.; Daodu OB; Department of Veterinary Microbiology, Virology Unit, Faculty of Veterinary Medicine, University of Ilorin, Ilorin, Kwara State, Nigeria.; Ige F; Centre for Human Virology and Genomics, Nigerian Institute of Medical Research, Yaba, Lagos State, Nigeria.; Adebajo S; International Research Centre of Excellence, Institute of Human Virology, Nigeria, Abuja, Nigeria.; Centre for International Health, Education, and Biosecurity (CIHEB), Maryland Global Initiatives Corporation (MGIC), University of Maryland, Abuja, Nigeria.; Igumbor EU; Centre for Infectious Diseases Research, Nigerian Institute of Medical Research, Yaba, Lagos State, Nigeria.; School of Health Systems and Public Health, University of Pretoria, Pretoria, South Africa.; Oladoye MJ; Centre for One Health and Zoonotic Diseases, Slum and Rural Health Initiative, Ibadan, Nigeria.; Shaibu JO; Centre for Human Virology and Genomics, Nigerian Institute of Medical Research, Yaba, Lagos State, Nigeria.; Ogoina D; Department of Internal Medicine, Infectious Diseases Unit, Niger Delta University Teaching Hospital, Bayelsa, Nigeria.; Audu RA; Centre for Human Virology and Genomics, Nigerian Institute of Medical Research, Yaba, Lagos State, Nigeria. |
| Source: | The Pan African medical journal [Pan Afr Med J] 2025 Jun 03; Vol. 50 (Suppl 1), pp. 14. Date of Electronic Publication: 2025 Jun 03 (Print Publication: 2025). |
| Publication Type: | Journal Article |
| Language: | English |
| Journal Info: | Publisher: African Field Epidemiology Network Country of Publication: Uganda NLM ID: 101517926 Publication Model: eCollection Cited Medium: Internet ISSN: 1937-8688 (Electronic) NLM ISO Abbreviation: Pan Afr Med J Subsets: MEDLINE |
| Imprint Name(s): | Original Publication: Kampala, Uganda : African Field Epidemiology Network |
| MeSH Terms: | Patient Acceptance of Health Care*/statistics & numerical data ; Malaria Vaccines*/administration & dosage ; Vaccination*/statistics & numerical data ; Malaria, Falciparum*/prevention & control ; Malaria, Falciparum*/epidemiology ; Health Knowledge, Attitudes, Practice*; Nigeria/epidemiology ; Humans ; Cross-Sectional Studies ; Female ; Male ; Adult ; Surveys and Questionnaires ; Young Adult ; Middle Aged ; Adolescent ; Endemic Diseases |
| Abstract: | Introduction: Nigeria ranks second in Africa for the highest number of mpox cases. This study aimed to evaluate the knowledge and awareness of mpox among Nigerians living in endemic regions and their willingness to accept the mpox vaccine when available.; Methods: we conducted a cross-sectional study using a multi-stage sampling technique. Data was collected from eligible individuals in Bayelsa, Delta, Lagos, and Rivers, Nigeria, between September 1 and November 30, 2023, using a standardized structured questionnaire. Descriptive analysis was conducted, and inferential analyses were performed using binary logistic regression (p < 0.05).; Results: five hundred and twenty-four (524) persons with a mean age of 33.9 ± 10.4 years participated in this study. Fifty-eight percent (58%) were aware of mpox, and 15.5% of participants had heard about the mpox vaccine. Participants from Delta State were 70 percent less likely, while those from Lagos and Rivers States were 2.5 times and 1.04 times, respectively (OR= 2.48, p=0.012; OR= 1.04, p=0.89) more likely to receive the mpox vaccine when compared with participants from Bayelsa State. Eighty-four (84.5%) of respondents were unwilling to take the vaccine if they had to pay for it.; Conclusion: although many people were aware of the mpox infection, only a few people were aware of the vaccine. Health intervention programs to improve knowledge of mpox and increase the uptake of mpox vaccines should be co-designed with community stakeholders, while mpox vaccines, when available, should be made accessible at subsidized or at no cost to Nigerians to improve uptake.; (©Isaac Iyinoluwa Olufadewa et al.) |
| Competing Interests: | The authors declare no competing interests. |
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| Contributed Indexing: | Keywords: Knowledge; Nigeria; awareness; endemic; mpox vaccine; mpox virus |
| Substance Nomenclature: | 0 (Malaria Vaccines) |
| Entry Date(s): | Date Created: 20260126 Date Completed: 20260126 Latest Revision: 20260128 |
| Update Code: | 20260130 |
| PubMed Central ID: | PMC12831209 |
| DOI: | 10.11604/pamj.supp.2025.50.1.44293 |
| PMID: | 41585782 |
| Database: | MEDLINE |
Journal Article