Long-term outcomes after ostial stenting for 0.0.1 and 0.1.0 coronary bifurcation lesions. Results from the real-world multicenter registry.
| Title: | Long-term outcomes after ostial stenting for 0.0.1 and 0.1.0 coronary bifurcation lesions. Results from the real-world multicenter registry. |
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| Authors: | Khelimskii D; FSBI National Medical Research Center named after E N Meshalkin Center of Oncology and Radiotherapy, Russian Federation. Electronic address: d_helimskij@meshalkin.ru.; Bessonov I; Tyumen Cardiology Research Center Branch of Tomsk National Medical Research Center, Russian Federation.; Kashtanov M; Tyumen Cardiology Research Center Branch of Tomsk National Medical Research Center, Russian Federation.; Sapozhnikov S; Tyumen Cardiology Research Center Branch of Tomsk National Medical Research Center, Russian Federation.; Utegenov R; Tyumen Cardiology Research Center Branch of Tomsk National Medical Research Center, Russian Federation.; Manukian S; FSBI National Medical Research Center named after E N Meshalkin, Russian Federation.; Badoian A; FSBI National Medical Research Center named after E N Meshalkin, Russian Federation.; Baranov A; FSBI National Medical Research Center named after E N Meshalkin, Russian Federation.; Krestyaninov O; FSBI National Medical Research Center named after E N Meshalkin, Russian Federation. |
| Source: | Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheorese [Hellenic J Cardiol] 2026 Feb 18. Date of Electronic Publication: 2026 Feb 18. |
| Publication Model: | Ahead of Print |
| Publication Type: | Journal Article |
| Language: | English |
| Journal Info: | Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 101257381 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2241-5955 (Electronic) Linking ISSN: 11099666 NLM ISO Abbreviation: Hellenic J Cardiol Subsets: MEDLINE |
| Imprint Name(s): | Publication: [Amsterdam] : Elsevier B.V.; Original Publication: Athens, Greece : Hellenic Cardiological Society |
| Abstract: | Background: Although cross-over stenting (CS) remains the gold standard for treating most bifurcation lesions, ostial stenting (OS) may be considered for patients with favorable anatomy. The aim of this study was to evaluate outcomes after OS vs. CS in patients with 0.1.0 and 0.0.1 bifurcation lesions.; Methods: A total of 790 patients who underwent PCI for 0.1.0 and 0.0.1 lesions and had clinical follow-up were included in the analysis. The patients were divided into an OS group (n = 186) and CS group (n = 604). An inverse probability treatment weighting model was used to assess long-term outcomes.; Results: OS was more often performed in patients with left main disease (52% vs. 31%, p < 0.001). Patients in the OS group more often had calcification (23% vs. 15%, p = 0.026) and thrombosis (11% vs. 6.5%, p = 0.044). The occurrence of residual dissection was significantly lower in the OS group (0.2% vs. 3.1%, p = 0.007) in addition to disturbance of blood flow in the SB after stent implantation (0.5% vs. 3.2% p = 0.007). The median follow-up was 1504 days. There were no significant differences in the major adverse cardiac events (MACE) between groups (18.9% vs. 22.2%, p = 0.331). However, a lower rate of target vessel revascularization (TVR) was observed in the OS group (2.4% vs. 0.5%, p = 0.046).; Conclusions: In patients with 0.0.1 and 0.1.0 bifurcation lesions, OS was associated with less residual stenosis and lower incidence of blood flow disturbance in the SB after stent implantation, and a lower incidence of TVR at follow-up than was the CS, but this finding was not accompanied by a reduction in the rates of MACE.; (Copyright © 2026 Hellenic Society of Cardiology. Publishing services by Elsevier Inc. All rights reserved.) |
| Competing Interests: | Declaration of interest The authors declare no conflict of interest. |
| Contributed Indexing: | Keywords: Coronary artery stenting; Coronary bifurcation lesion; Crossover stenting; Medina classification; Ostial stenting |
| Entry Date(s): | Date Created: 20260220 Latest Revision: 20260306 |
| Update Code: | 20260307 |
| DOI: | 10.1016/j.hjc.2026.02.002 |
| PMID: | 41720400 |
| Database: | MEDLINE |
Journal Article