Multimodal analysis of cell-free DNA to improve early detection of gastric cancer.
| Title: | Multimodal analysis of cell-free DNA to improve early detection of gastric cancer. |
|---|---|
| Authors: | Long VD; Department of Gastrointestinal Surgery, University Medical Center, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh, Vietnam.; Department of General Surgery, Faculty of Medicine, University of Medicine and Pharmacy, Ho Chi Minh, Vietnam.; Huynh LAK; Medical Genetics Institute, Ho Chi Minh, Vietnam.; Vo DH; Medical Genetics Institute, Ho Chi Minh, Vietnam.; Nguyen THH; Medical Genetics Institute, Ho Chi Minh, Vietnam.; Van TTV; Medical Genetics Institute, Ho Chi Minh, Vietnam.; Nguyen GTH; Medical Genetics Institute, Ho Chi Minh, Vietnam.; Doan TN; Department of Gastrointestinal Surgery, University Medical Center, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh, Vietnam.; Nguyen VH; Department of Gastrointestinal Surgery, University Medical Center, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh, Vietnam.; Tran QD; Department of Gastrointestinal Surgery, University Medical Center, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh, Vietnam.; Dang QT; Department of Gastrointestinal Surgery, University Medical Center, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh, Vietnam.; Nguyen VTA; Department of General Surgery, Faculty of Medicine, University of Medicine and Pharmacy, Ho Chi Minh, Vietnam.; Ho LMQ; Department of Gastrointestinal Surgery, University Medical Center, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh, Vietnam.; Ha TPD; Ha Noi Medical University Hospital, Hanoi, Vietnam.; Dang TND; Ha Noi Medical University Hospital, Hanoi, Vietnam.; Nguyen PTN; Da Nang Oncology Hospital, Da Nang, Vietnam.; Nguyen KT; Nghe An Oncology Hospital, Vinh City, Nghe An, Vietnam.; Ho VC; Nghe An Oncology Hospital, Vinh City, Nghe An, Vietnam.; Le TL; Thai Nguyen Central General Hospital, Thai Nguyen, Vietnam.; Nguyen THN; Thai Nguyen Central General Hospital, Thai Nguyen, Vietnam.; Tu NH; Buon Ma Thuot Medical University, Buon Ma Thuot, Vietnam.; Tran TS; Buon Ma Thuot Medical University, Buon Ma Thuot, Vietnam.; Jasmine TX; Medic Medical Center, Ho Chi Minh, Vietnam.; Vo TL; Medic Medical Center, Ho Chi Minh, Vietnam.; Nai THT; Medic Medical Center, Ho Chi Minh, Vietnam.; Tran TT; Medic Medical Center, Ho Chi Minh, Vietnam.; Truong MH; Medic Medical Center, Ho Chi Minh, Vietnam.; Tran NC; Medic Medical Center, Ho Chi Minh, Vietnam.; Nguyen TC; Military Medical Hospital 175, Ho Chi Minh, Vietnam.; Nguyen TT; Military Medical Hospital 175, Ho Chi Minh, Vietnam.; Le BT; Can Tho Oncology Hospital, Can Tho, Vietnam.; Tang VP; Can Tho Oncology Hospital, Can Tho, Vietnam.; Nguyen TT; Medical Genetics Institute, Ho Chi Minh, Vietnam.; Nguyen AT; Medical Genetics Institute, Ho Chi Minh, Vietnam.; Vu HG; Medical Genetics Institute, Ho Chi Minh, Vietnam.; Van Phan T; Medical Genetics Institute, Ho Chi Minh, Vietnam.; Nguyen TNT; Medical Genetics Institute, Ho Chi Minh, Vietnam.; Cao HA; Medical Genetics Institute, Ho Chi Minh, Vietnam.; Nguyen TH; Medical Genetics Institute, Ho Chi Minh, Vietnam.; Tu LN; Medical Genetics Institute, Ho Chi Minh, Vietnam.; Giang H; Medical Genetics Institute, Ho Chi Minh, Vietnam.; Phan MD; Medical Genetics Institute, Ho Chi Minh, Vietnam.; Nguyen HN; Medical Genetics Institute, Ho Chi Minh, Vietnam.; Nguyen VTC; Medical Genetics Institute, Ho Chi Minh, Vietnam. chinguyen@genesolutions.vn.; Tran LS; Medical Genetics Institute, Ho Chi Minh, Vietnam. leson1808@gmail.com. |
| Source: | BMC cancer [BMC Cancer] 2026 Feb 23; Vol. 26 (1). Date of Electronic Publication: 2026 Feb 23. |
| Publication Type: | Journal Article |
| Language: | English |
| Journal Info: | Publisher: BioMed Central Country of Publication: England NLM ID: 100967800 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2407 (Electronic) Linking ISSN: 14712407 NLM ISO Abbreviation: BMC Cancer Subsets: MEDLINE; In Process |
| Imprint Name(s): | Original Publication: London : BioMed Central, [2001- |
| Competing Interests: | Declarations. Ethics approval and consent to participate: This study received approval from the Institutional Review Board, University Medical Center at Ho Chi Minh city, as well as the Medical Genetics Institute in Ho Chi Minh City, Vietnam (ID: 79/GCN-HĐĐĐ). Informed written consent was obtained from each participant in accordance with the Declaration of Helsinki. Consent for publication: Not applicable. Competing interests: The authors, including LST, HG, MDP, and HNN, hold equity in Gene Solutions. HG, MDP, and LST are listed as inventors on the patent application (USPTO 17930705). We confirm that this does not impact on our compliance with the journal's policies regarding data and material sharing. |
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(PMID: 388499051115770710.1186/s13073-024-01352-1) |
| Contributed Indexing: | Keywords: CfDNA; Gastric cancer; Hotspot mutations; Methylation and fragmentomic |
| Entry Date(s): | Date Created: 20260223 Latest Revision: 20260402 |
| Update Code: | 20260507 |
| PubMed Central ID: | PMC13036984 |
| DOI: | 10.1186/s12885-026-15720-0 |
| PMID: | 41731447 |
| Database: | MEDLINE |
Journal Article