Defining Inactivity of Juvenile Spondyloarthropathies: Delphi Study Among Pediatric Rheumatology Academy (PeRA) From Türkiye.
| Title: | Defining Inactivity of Juvenile Spondyloarthropathies: Delphi Study Among Pediatric Rheumatology Academy (PeRA) From Türkiye. |
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| Authors: | Türkuçar S; Pamukkale University, Division of Pediatric Rheumatology, Denizli Province, Turkey.; Sözeri B; University of Health Sciences, Umraniye Research and Training Hospital, Department of Pediatric Rheumatology, İstanbul, Turkey.; Sönmez HE; Kocaeli University, Faculty of Medicine, Department of Pediatric Rheumatology, Kocaeli, Turkey.; Şahin N; Kocaeli University, Faculty of Medicine, Department of Pediatric Rheumatology, Kocaeli, Turkey.; Açarı C; Malatya İnönü University, Department of Pediatric Rheumatology, Malatya, Turkey.; Dundar HA; University of Health Sciences, Izmir Behçet Uz Children Hospital, Department of Pediatric Rheumatology, Izmir, Turkey.; İşgüder R; University of Health Sciences, Adana City Hospital, Department of Pediatric Rheumatology, Adana, Turkey.; Gücenmez ÖA; University of Health Sciences, Izmir Behçet Uz Children Hospital, Department of Pediatric Rheumatology, Izmir, Turkey.; Taşkın SN; University of Health Sciences, Eskişehir City Hospital, Department of Pediatric Rheumatology, Eskişehir, Turkey.; Çakan M; University of Health Sciences, İstanbul Zeynep Kamil Training and Research Hospital, Department of Pediatric Rheumatology, İstanbul, Turkey.; Demir F; İstanbul Acıbadem Hospital, Department of Pediatric Rheumatology, İstanbul, Turkey.; Şener S; University of Health Sciences, Adana City Hospital, Department of Pediatric Rheumatology, Adana, Turkey.; Karadağ ŞG; University of Health Sciences, İstanbul Bakırköy Sadi Konuk Hospital, Department of Pediatric Rheumatology, İstanbul, Turkey.; Yıldırım DG; Gazi University, Department of Pediatric Rheumatology, Ankara, Turkey.; Kazanasmaz H; Karadeniz Technical University, Department of Pediatric Rheumatology, Trabzon, Turkey.; Öztürk K; University of Health Sciences, İstanbul Medeniyet University, Department of Pediatric Rheumatology, İstanbul, Turkey.; Yener GO; University of Health Sciences, Eskişehir City Hospital, Department of Pediatric Rheumatology, Eskişehir, Turkey.; Tanatar A; Marmara University, Department of Pediatric Rheumatology, İstanbul, Turkey.; Doğantan Ş; University of Health Sciences, İstanbul Başakşehir Çam and Sakura City Hospital, Department of Pediatric Rheumatology, İstanbul, Turkey.; Taşkın RB; İzmir Tepecik Training and Research Hospital, Department of Pediatric Rheumatology, İzmir, Turkey.; Bağlan E; University of Health Sciences, Ankara Etlik City Hospital, Department of Pediatric Rheumatology, Ankara, Turkey.; Demir BK; University of Health Sciences, İzmir City Hospital, Department of Pediatric Rheumatology, İzmir, Turkey.; Bora B; Dokuz Eylul University, Department of Pediatric Rheumatology, İzmir, Turkey.; Kalyoncu M; Karadeniz Technical University, Department of Pediatric Rheumatology, Trabzon, Turkey.; Bakkaloğlu S; Gazi University, Department of Pediatric Rheumatology, Ankara, Turkey.; Ünsal E; Dokuz Eylul University, Department of Pediatric Rheumatology, İzmir, Turkey.; Yüksel S; Çanakkale Onsekiz Mart University, Department of Pediatric Rheumatology, İzmir, Turkey. |
| Source: | International journal of rheumatic diseases [Int J Rheum Dis] 2026 Mar; Vol. 29 (3), pp. e70606. |
| Publication Type: | Journal Article |
| Language: | English |
| Journal Info: | Publisher: Wiley on behalf of the Asia Pacific League of Associations for Rheumatology Country of Publication: England NLM ID: 101474930 Publication Model: Print Cited Medium: Internet ISSN: 1756-185X (Electronic) Linking ISSN: 17561841 NLM ISO Abbreviation: Int J Rheum Dis Subsets: MEDLINE |
| Imprint Name(s): | Original Publication: [Oxford, UK] : Wiley on behalf of the Asia Pacific League of Associations for Rheumatology |
| MeSH Terms: | Rheumatology*/standards ; Spondylarthropathies*/physiopathology ; Spondylarthropathies*/diagnosis ; Disability Evaluation*; Humans ; Delphi Technique ; Consensus ; Predictive Value of Tests ; Turkey ; Child ; Severity of Illness Index ; Female ; Male ; Rheumatologists ; Adolescent ; Prognosis ; Magnetic Resonance Imaging |
| Abstract: | Introduction: Juvenile spondyloarthropathies (JSpA) are a group of chronic inflammatory diseases that differ in their clinical features and course from adult spondyloarthropathies and other subtypes of juvenile idiopathic arthritis (JIA). Therefore, defining disease inactivity in JSpA requires specific criteria. This Delphi study aimed to establish a national consensus on its core clinical, laboratory, and radiological domains.; Methods: A total of 27 pediatric rheumatologists participated in the Delphi survey, conducted in two rounds. Participants were asked multiple-choice and Likert-type questions regarding their preferences for using domains including anamnesis, laboratory findings, imaging methods, and predefined disease activity scores for assessing inactivity. At the end of each round, the study coordinators determined the "strong consensus" items based on a power analysis of these parameters.; Results: The absence of "pain or tenderness in the peripheral joints, lower back and entheseal regions" in anamnesis domain and "tenderness in the peripheral joints, entheseal areas, and hip examination"; "swelling in the peripheral joints; tenderness on sacroiliac compression testing"; and "no reduction in hip RoM examination" in physical examination domain received the highest scores and were accepted as strong consensus. Furthermore, normalization of MRI findings of SIJ and hip/peripheral joint and "physician global score = 0" reached the specified thresholds, resulting in strong consensus following the second round.; Conclusions: This Delphi study highlights the need for a multidimensional approach that integrates clinical, radiological, and physician assessments to define disease inactivity in patients with JSpA. The resulting consensus provides a more specific assessment on inactivity defining JSpA patients and reflects a national consensus.; (© 2026 Asia Pacific League of Associations for Rheumatology and John Wiley & Sons Australia, Ltd.) |
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| Contributed Indexing: | Keywords: Delphi; MRI; inactivity; juvenile; spondylarthritis |
| Entry Date(s): | Date Created: 20260313 Date Completed: 20260313 Latest Revision: 20260313 |
| Update Code: | 20260313 |
| DOI: | 10.1111/1756-185x.70606 |
| PMID: | 41821199 |
| Database: | MEDLINE |
Journal Article