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The integration of Mn and Co redox couples endowed MnCo2O4-modified electrochemical sensing platform for ultrasensitive detection of Carbendazim residue in fruit and vegetable samples.

Title: The integration of Mn and Co redox couples endowed MnCo2O4-modified electrochemical sensing platform for ultrasensitive detection of Carbendazim residue in fruit and vegetable samples.
Authors: Huyen NN; Phenikaa University Nano Institute (PHENA), Phenikaa School of Engineering (PSE), Phenikaa University, Hanoi 12116, Viet Nam. Electronic address: huyen.nguyenngoc@phenikaa-uni.edu.vn.; Dinh NX; Phenikaa University Nano Institute (PHENA), Phenikaa School of Engineering (PSE), Phenikaa University, Hanoi 12116, Viet Nam.; Mai VTH; Phenikaa University Nano Institute (PHENA), Phenikaa School of Engineering (PSE), Phenikaa University, Hanoi 12116, Viet Nam.; Huong PTL; Phenikaa University Nano Institute (PHENA), Phenikaa School of Engineering (PSE), Phenikaa University, Hanoi 12116, Viet Nam.; Toan ND; Centre for Quantum Electronics, Institute of Physics, Vietnam Academy of Science and Technology, Hanoi 11113, Viet Nam.; Son NA; Vicostone Joint Stock Company, Phenikaa Group, Hanoi 10000, Viet Nam.; Pham-Cong; Department of Nanoenergy Engineering and College of Nanoscience and Nanotechnology, Pusan National University, Busan 46241, Republic of Korea.; Tran VT; Faculty of Biotechnology, Chemistry and Environmental Engineering, Phenikaa School of Engineering (PSE), Phenikaa University, Hanoi 12116, Viet Nam.; Van Tuan H; Phenikaa University Nano Institute (PHENA), Phenikaa School of Engineering (PSE), Phenikaa University, Hanoi 12116, Viet Nam.; Hoa NQ; Faculty of Physics, VNU University of Science, Vietnam National University, Hanoi 11416, Viet Nam.; Thang PD; Faculty of Physics, VNU University of Science, Vietnam National University, Hanoi 11416, Viet Nam.; Le AT; Phenikaa University Nano Institute (PHENA), Phenikaa School of Engineering (PSE), Phenikaa University, Hanoi 12116, Viet Nam. Electronic address: tuan.leanh@phenikaa-uni.edu.vn.
Source: Food chemistry [Food Chem] 2026 May 30; Vol. 512, pp. 148867. Date of Electronic Publication: 2026 Mar 14.
Publication Type: Journal Article; Evaluation Study
Language: English
Journal Info: Publisher: Elsevier Applied Science Publishers Country of Publication: England NLM ID: 7702639 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-7072 (Electronic) Linking ISSN: 03088146 NLM ISO Abbreviation: Food Chem Subsets: MEDLINE
Imprint Name(s): Publication: Barking : Elsevier Applied Science Publishers; Original Publication: Barking, Eng., Applied Science Publishers.
MeSH Terms: Vegetables*/chemistry ; Fruit*/chemistry ; Electrochemical Techniques*/instrumentation ; Electrochemical Techniques*/methods ; Cobalt*/chemistry ; Carbamates*/analysis ; Carbamates*/chemistry ; Manganese*/chemistry ; Benzimidazoles*/analysis ; Benzimidazoles*/chemistry ; Oxides*/chemistry ; Pesticide Residues*/analysis ; Pesticide Residues*/chemistry; Food Contamination/analysis ; Manganese Compounds/chemistry ; Oxidation-Reduction ; Limit of Detection
Abstract: This study reports the carbendazim (CBZ) detecting capability of spinel cobaltite MnCo2O4 (MCO) synthesized via a microwave-assisted hydrothermal approach. The MCO-modified screen-printed electrode (MCO/SPE) exhibited excellent electrocatalytic activity toward CBZ oxidation. As a result, the proposed sensor enables sensitive CBZ detection over two distinct linear ranges (0.05-5 μM and 25-500 μM), with a low detection limit of 0.02 μM and a high sensitivity of 6.46 μA μM-1 cm-2. The enhanced sensing performance is attributed to the synergistic redox activity of Co2+/Co3+ and Mn2+/Mn3+ couples, which enhance both electrical conductivity and catalytic activity, together with the nanorod morphology that promotes efficient diffusion of CBZ molecules and electrolyte species. The applicability of the MCO/SPE was further validated through effective CBZ detection in fruit and vegetable samples as compared with the liquid chromatography-tandem mass spectrometry (LC-MS/MS) method, showing strong potential for food safety monitoring.; (Copyright © 2026 Elsevier Ltd. All rights reserved.)
Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
Contributed Indexing: Keywords: Carbendazim; Electrochemical sensor; MnCo(2)O(4); Pesticide residue; Spinel structures
Substance Nomenclature: 3G0H8C9362 (Cobalt); 0 (Carbamates); 42Z2K6ZL8P (Manganese); H75J14AA89 (carbendazim); 0 (Benzimidazoles); 0 (Oxides); 0 (Pesticide Residues); 0 (Manganese Compounds)
Entry Date(s): Date Created: 20260318 Date Completed: 20260504 Latest Revision: 20260504
Update Code: 20260504
DOI: 10.1016/j.foodchem.2026.148867
PMID: 41850109
Database: MEDLINE

Journal Article; Evaluation Study