Ovophis tonkinensis envenoming presenting with severe isolated thrombocytopenia and local necrosis: A case report.
| Title: | Ovophis tonkinensis envenoming presenting with severe isolated thrombocytopenia and local necrosis: A case report. |
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| Authors: | Duc ND; Toxicologist, Poison Control Center, Bach Mai Hospital, Hanoi, Vietnam.; Hong Anh LN; Lecturer, Department of Internal Medicine, Thai Nguyen University of Medicine and Pharmacy, Thai Nguyen, Vietnam.; Hong Khanh LN; Lecturer, Department of Internal Medicine, Vinh University of Medicine and Pharmacy, Nghe An, Vietnam.; Bach ND; Lecturer, Department of Internal Medicine, Hanoi Medical University, Hanoi, Vietnam. |
| Source: | Tropical doctor [Trop Doct] 2026 Mar 26, pp. 494755261435153. Date of Electronic Publication: 2026 Mar 26. |
| Publication Model: | Ahead of Print |
| Publication Type: | Journal Article |
| Language: | English |
| Journal Info: | Publisher: Sage Country of Publication: England NLM ID: 1301706 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1758-1133 (Electronic) Linking ISSN: 00494755 NLM ISO Abbreviation: Trop Doct Subsets: MEDLINE |
| Imprint Name(s): | Publication: Oct. 2012- : London : Sage; Original Publication: -July 2012 : London, Royal Society of Medicine |
| Abstract: | Pit viper envenoming commonly causes venom-induced consumption coagulopathy with hypofibrinogenaemia. However, isolated thrombocytopenia without fibrinogen depletion is less recognised and may alter transfusion strategy. We report a confirmed Ovophis tonkinensis bite from northern Vietnam presenting with severe isolated thrombocytopenia and local necrosis. The case highlights the importance of serial platelet monitoring, awareness of fibrinogen availability and appropriate timing of antivenom and platelet support in resource-limited tropical settings. |
| Contributed Indexing: | Keywords: Ovophis tonkinensis; Vietnam; antivenom; necrosis; snakebite; thrombocytopenia |
| Entry Date(s): | Date Created: 20260326 Latest Revision: 20260326 |
| Update Code: | 20260326 |
| DOI: | 10.1177/00494755261435153 |
| PMID: | 41885395 |
| Database: | MEDLINE |
Journal Article