Thyroid Monitoring After Intravascular Iodinated Contrast Media in Infants and Children Through 3 Years of Age.
| Title: | Thyroid Monitoring After Intravascular Iodinated Contrast Media in Infants and Children Through 3 Years of Age. |
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| Authors: | Miller RS; Samuelson Children's Hospital at Sinai, Baltimore, Maryland.; Dillman JR; Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, Ohio.; Crystal MA; Columbia University Vagelos College of Physicians and Surgeons and New York-Presbyterian, New York, New York.; Bethin K; Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, New York, Buffalo, New York.; Dinauer CA; Yale School of Medicine, New Haven, Connecticut.; Forbes-Amrein M; Indiana University School of Medicine, Indianapolis, Indiana.; Gordon BM; Rady Children's Hospital, University of California San Diego, San Diego, California.; Hughes B; Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, New York, Buffalo, New York.; Lahoti A; Nationwide Children's Hospital, Columbus, Ohio.; Marshall AC; The Hospital for Sick Children, Toronto, Ontario, Canada.; Mastrandrea LD; Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, New York, Buffalo, New York.; Pesce LM; University of Iowa Carver College of Medicine, Iowa City, Iowa.; Rapaport R; Icahn School of Medicine at Mount Sinai, New York, New York.; Salavitabar A; Nationwide Children's Hospital, Columbus, Ohio.; Wasserman JD; Perelman School of Medicine, University of Pennsylania, Philadelphia, Pennsylvania.; Bauer AJ; Perelman School of Medicine, University of Pennsylania, Philadelphia, Pennsylvania.; Wassner AJ; Harvard Medical School, Boston, Massachusetts. |
| Source: | Pediatrics [Pediatrics] 2026 May 01; Vol. 157 (5). |
| Publication Type: | Journal Article; Review |
| Language: | English |
| Journal Info: | Publisher: American Academy of Pediatrics Country of Publication: United States NLM ID: 0376422 Publication Model: Print Cited Medium: Internet ISSN: 1098-4275 (Electronic) Linking ISSN: 00314005 NLM ISO Abbreviation: Pediatrics Subsets: MEDLINE |
| Imprint Name(s): | Publication: Elk Grove Village Il : American Academy of Pediatrics; Original Publication: Springfield, Ill., Thomas. |
| MeSH Terms: | Contrast Media*/adverse effects ; Contrast Media*/administration & dosage ; Thyroid Gland*/drug effects ; Thyroid Diseases*/chemically induced ; Thyroid Diseases*/diagnosis ; Iodine*/adverse effects ; Iodine*/administration & dosage ; Thyroid Function Tests*; Humans ; Child, Preschool ; Infant |
| Abstract: | In March 2022, the US Food and Drug Administration issued a drug safety communication (DSC) recommending monitoring of thyroid function in children up to 3 years of age who receive intravascular injection of iodinated contrast media (IV ICM) for medical imaging. In response, a group of pediatric and imaging experts convened to review the current scientific evidence on thyroid dysfunction after IV ICM and to provide recommendations on thyroid testing and management after IV ICM administration in infants and children. There are considerable gaps in knowledge related to the risk of thyroid dysfunction in young children exposed to IV ICM, and we strongly recommend that high-quality prospective studies be proposed and funded to clarify the incidence, risk modifiers, natural history, and outcomes of thyroid dysfunction after IV ICM exposure in this population.; (Copyright © 2026 by the American Academy of Pediatrics.) |
| Substance Nomenclature: | 0 (Contrast Media); 9679TC07X4 (Iodine) |
| Entry Date(s): | Date Created: 20260426 Date Completed: 20260430 Latest Revision: 20260430 |
| Update Code: | 20260501 |
| DOI: | 10.1542/peds.2026-076640 |
| PMID: | 42036119 |
| Database: | MEDLINE |
Journal Article; Review