Imaging of pulmonary vascular disease by intravascular ultrasound.
| Title: | Imaging of pulmonary vascular disease by intravascular ultrasound. |
|---|---|
| Authors: | Scott PJ; Non-Invasive Heart Unit, Killingbeck Hospital, Leeds, West Yorkshire, UK.; Essop AR; al-Ashab W; Deaner A; Parsons J; Williams G |
| Source: | International journal of cardiac imaging [Int J Card Imaging] 1993 Sep; Vol. 9 (3), pp. 179-84. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Language: | English |
| Journal Info: | Publisher: Kluwer Academic Publishers Country of Publication: Netherlands NLM ID: 8600426 Publication Model: Print Cited Medium: Print ISSN: 0167-9899 (Print) Linking ISSN: 01679899 NLM ISO Abbreviation: Int J Card Imaging Subsets: MEDLINE |
| Imprint Name(s): | Publication: Dordrecht : Kluwer Academic Publishers; Original Publication: Boston : Nijhoff, 1985-c2000. |
| MeSH Terms: | Ultrasonography, Interventional*; Hypertension, Pulmonary/*diagnostic imaging ; Pulmonary Artery/*diagnostic imaging; Hypertension, Pulmonary/physiopathology ; Pulmonary Artery/physiopathology ; Adolescent ; Adult ; Cardiac Catheterization ; Child ; Chronic Disease ; Humans ; Middle Aged ; Prospective Studies ; Pulmonary Wedge Pressure ; Vascular Resistance |
| Abstract: | To assess the ability of intravascular ultrasound (IVUS) to image changes in the pulmonary arterial wall associated with pulmonary hypertension (PHT), 10 subjects requiring diagnostic right and left heart catheterization were studied. In addition to measurements of pulmonary artery pressure and pulmonary vascular resistance and pulmonary angiography, when indicated, all underwent simultaneous IVUS imaging in the pulmonary arterial system using a 20 MHz ultrasound transducer mounted on a 2 mm diameter catheter. Four patients had normal pulmonary artery pressures and 6 had varying degrees of PHT. Satisfactory ultrasound images were obtained in 9 out of the 10 patients. In those with normal pulmonary artery pressures ultrasound showed a thin vessel wall with no distinction between separate layers. In patients with systemic PHT, a three-layered vessel wall was apparent and areas compatible with intimal proliferation were seen. In a patient with pulmonary embolic disease areas consistent with mural thrombus were detected at sites of luminal narrowing on the pulmonary angiogram. IVUS is capable of imaging some of the morphological changes in the wall of the pulmonary artery known to occur in longstanding PHT and may therefore become a useful adjunct to haemodynamic measurements and pulmonary angiography for the in vivo assessment of pulmonary vascular disease. |
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| Entry Date(s): | Date Created: 19930901 Date Completed: 19940321 Latest Revision: 20191101 |
| Update Code: | 20260130 |
| DOI: | 10.1007/BF01145319 |
| PMID: | 8106796 |
| Database: | MEDLINE |
Journal Article; Research Support, Non-U.S. Gov't