[Physico-chemical properties of microbial antigens and the immuno-allergic tests].
| Title: | [Physico-chemical properties of microbial antigens and the immuno-allergic tests]. |
|---|---|
| Transliterated Title: | Fiziko-khimicheskie svoĭstva mikrobnykh antigenov i immuno-allergicheskie testy. |
| Authors: | Beklemishev ND; Sukhodoeva GS; Bul'vakhter IaL; Shin NG |
| Source: | Biulleten' eksperimental'noi biologii i meditsiny [Biull Eksp Biol Med] 1978 Mar; Vol. 85 (3), pp. 322-5. |
| Publication Type: | Comparative Study; Journal Article |
| Language: | Russian |
| Journal Info: | Publisher: Administrativnoia Zdaniia Minzdrava Sssr Country of Publication: Russia (Federation) NLM ID: 0370627 Publication Model: Print Cited Medium: Print ISSN: 0365-9615 (Print) Linking ISSN: 03659615 NLM ISO Abbreviation: Biull Eksp Biol Med Subsets: MEDLINE |
| Imprint Name(s): | Publication: Moskva : Administrativnoia Zdaniia Minzdrava Sssr; Original Publication: Moskva, Medgiz. |
| MeSH Terms: | Skin Tests*/methods; Antigens, Bacterial/*analysis ; Brucella abortus/*immunology ; Brucellosis/*immunology; Bacterial Proteins/immunology ; Hypersensitivity, Delayed/diagnosis ; Hypersensitivity, Immediate/diagnosis ; Polysaccharides, Bacterial/immunology ; RNA, Bacterial/immunology ; Animals ; Female ; Guinea Pigs ; Male |
| Abstract: | Experiments were conducted on guinea pigs sensitized by the delayed and immediate types of allergy. Different antigens obtained from the strain of Brucella abortus BA-19 were used for sensitization and the resolving action. Comparison of the resolving properties of the corpuscular, soluble (ultrasound treated) antigens and purified protein fractions, polysaccharide and RNA was carried out in the skin reactions of the immediate and delayed type, passive skin anaphylaxis, acute anaphylactic shock, and the Schults-Dale test. Immediate reactions to the purified protein fraction were weaker than those to the whole soluble antigen, by which the animals were sensitized. Polysaccharide and the RNA-fractions proved to be inactive in the allergic reactions. |
| Substance Nomenclature: | 0 (Antigens, Bacterial); 0 (Bacterial Proteins); 0 (Polysaccharides, Bacterial); 0 (RNA, Bacterial) |
| Entry Date(s): | Date Created: 19780301 Date Completed: 19780915 Latest Revision: 20201209 |
| Update Code: | 20260130 |
| PMID: | 96888 |
| Database: | MEDLINE |
Comparative Study; Journal Article