| Title: |
The Profiles and Correlates of Psychopathology in Adolescents and Adults with Williams, Fragile X and Prader-Willi Syndromes |
| Language: |
English |
| Authors: |
Royston, R. (ORCID 0000-0002-9901-2284); Oliver, C.; Howlin, P.; Dosse, A.; Armitage, P.; Moss, J.; Waite, J. |
| Source: |
Journal of Autism and Developmental Disorders. Mar 2020 50(3):893-903. |
| Availability: |
Springer. Available from: Springer Nature. 233 Spring Street, New York, NY 10013. Tel: 800-777-4643; Tel: 212-460-1500; Fax: 212-348-4505; e-mail: customerservice@springernature.com; Web site: https://link.springer.com/ |
| Peer Reviewed: |
Y |
| Page Count: |
11 |
| Publication Date: |
2020 |
| Document Type: |
Journal Articles; Reports - Research |
| Descriptors: |
Psychopathology; Genetic Disorders; Correlation; Predictor Variables; Perceptual Impairments; Mental Disorders; Anxiety; Hyperactivity; Symptoms (Individual Disorders); Behavior Disorders |
| DOI: |
10.1007/s10803-019-04317-1 |
| ISSN: |
0162-3257 |
| Abstract: |
Psychopathology is prevalent in Williams (WS), fragile X (FXS) and Prader-Willi (PWS) syndromes. However, little is known about the potential correlates of psychopathology in these groups. A questionnaire study was completed by 111 caregivers of individuals with WS (n = 35); FXS (n = 50) and PWS (n = 26). Mean age was 26 years (range 12-57 years); 74 (67%) were male. Multiple regression analyses indicated that higher rates of health problems and sensory impairments predicted higher psychopathology in WS (p < 0.0001). In PWS, poorer adaptive ability predicted higher overall psychiatric disturbance (p = 0.001), generalised anxiety (p = 0.006) and hyperactivity (p = 0.003). There were no significant predictors in FXS. This study highlights dissociations in the potential risk markers of psychopathology between genetic syndromes. Implications for intervention are discussed. |
| Abstractor: |
As Provided |
| Entry Date: |
2020 |
| Accession Number: |
EJ1243046 |
| Database: |
ERIC |