| Title: |
Validating the Communication and Symbolic Behavior Scales-Developmental Profile Infant-Toddler Checklist (CSBS-DP ITC) beyond Infancy in the CDKL5 Deficiency Disorder |
| Language: |
English |
| Authors: |
Jacinta Saldaris; Helen Leonard; Kingsley Wong; Peter Jacoby; Mary Spence; Eric D. Marsh; Tim A. Benke; Scott Demarest; Jenny Downs (ORCID 0000-0001-7358-9037) |
| Source: |
Journal of Autism and Developmental Disorders. 2024 54(7):2526-2535. |
| Availability: |
Springer. Available from: Springer Nature. One New York Plaza, Suite 4600, New York, NY 10004. Tel: 800-777-4643; Tel: 212-460-1500; Fax: 212-460-1700; e-mail: customerservice@springernature.com; Web site: https://link.springer.com/ |
| Peer Reviewed: |
Y |
| Page Count: |
10 |
| Publication Date: |
2024 |
| Sponsoring Agency: |
National Institutes of Health (NIH) (DHHS) |
| Contract Number: |
U01NS11431201A1 |
| Document Type: |
Journal Articles; Reports - Research |
| Descriptors: |
Validity; Infants; Toddlers; Check Lists; Intellectual Disability; Goodness of Fit; Reliability; Caregiver Attitudes; Scores; Epilepsy; Psychometrics; Profiles; Behavior Rating Scales; Communication Skills; Child Development |
| Assessment and Survey Identifiers: |
Communication and Symbolic Behavior Scales |
| DOI: |
10.1007/s10803-023-06002-w |
| ISSN: |
0162-3257; 1573-3432 |
| Abstract: |
CDKL5 deficiency disorder (CDD) results in early-onset epilepsy and lifelong cognitive and motor impairments. With no validated measure for communication in CDD, this study evaluated the psychometric properties of the Communication and Symbolic Behavior Scales-Developmental Profile Infant Toddler Checklist (CSBS-DP ITC). Caregivers (n = 150; affected individuals aged 1-29 years) completed the CSBS-DP ITC. Distribution of scores indicated a floor effect. There was poor divergent validity for the three-factor model but goodness of fit and convergent validity data were satisfactory for the one-factor model. Individuals with poorer overall functional abilities scored lower on the CSBS-DP ITC. Test-retest reliability was excellent. The floor effect could explain the very high reliability, suggesting problems as a sensitive outcome measure in clinical trials for CDD. |
| Abstractor: |
As Provided |
| Entry Date: |
2024 |
| Accession Number: |
EJ1433004 |
| Database: |
ERIC |