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Upskilling the Cell Therapy Manufacturing Workforce: Design, Implementation, and Evaluation of a Massive Open Online Course

Title: Upskilling the Cell Therapy Manufacturing Workforce: Design, Implementation, and Evaluation of a Massive Open Online Course
Language: English
Authors: Mingyu Yang; Flora J. Keumurian; Caleb Neufeld; Elizabeth Skrip; John Duguid; Humberto Vega-Mercado; Reeta P. Rao; Marsha W. Rolle; Stacy L. Springs; Jacqueline M. Wolfrum (ORCID 0000-0002-9125-828X); Paul W. Barone (ORCID 0000-0001-6802-6846); Krystyn J. Van Vliet
Source: Advances in Physiology Education. 2024 48(4):733-741.
Availability: American Physiological Society. 9650 Rockville Pike, Bethesda, MD 20814-3991. Tel: 301-634-7164; Fax: 301-634-7241; e-mail: webmaster@the-aps.org; Web site: https://www.physiology.org/journal/advances
Peer Reviewed: Y
Page Count: 9
Publication Date: 2024
Sponsoring Agency: National Institute of Standards and Technology (NIST) (DOC)
Contract Number: 70NANB17H002
Document Type: Journal Articles; Reports - Research
Descriptors: MOOCs; Microbiology; Manufacturing; Labor Force; Curriculum Design; Curriculum Implementation; Curriculum Evaluation; Drug Therapy; Partnerships in Education; Labor Force Development; Educational Resources; Feedback (Response)
DOI: 10.1152/advan.00077.2023
ISSN: 1043-4046; 1522-1229
Abstract: Cell therapies have gained prominence as a promising therapeutic modality for treating a range of diseases. Despite the recent clinical successes of cell therapy products, very few formal training programs exist for cell therapy manufacturing. To meet the demand for a well-trained workforce, we assembled a team of university researchers and industry professionals to develop an online course on the principles and practice of cell therapy manufacturing. The course covers the basic cell and systems physiology underlying cell therapy products, in addition to explaining end-to-end manufacturing from cell acquisition through to patient treatment, industrialization, and regulatory processes. As of September 2023, >10,000 learners have enrolled in the course, and >90% of respondents to the course exit survey indicated that they were "very likely" or "likely" to recommend the course to a peer. In this article, we discuss our experience in the collaborative design and implementation of the online course as well as lessons learned from quantitative and qualitative student feedback. We believe that this course can serve as a model for how academia and industry can collaborate to create innovative, scalable training programs to meet the demands of the modern biotechnology workforce.
Abstractor: As Provided
Entry Date: 2024
Accession Number: EJ1452657
Database: ERIC