| Title: |
Measurement Properties of the German Version of the Cambridge Examination for Mental Disorders of Older People with Down Syndrome and Others with Intellectual Disabilities (CAMDEX-DS) |
| Language: |
English |
| Authors: |
Sandra V. Loosli; Lennart C. Neumann; Elisabeth Wlasich; Catharina Prix; Laura Koll; Endy Weidinger; Jonathan Vöglein; Olivia Wagemann; Adrian Danek; Georg Nübling; Johannes Levin |
| Source: |
Journal of Intellectual & Developmental Disability. 2024 49(4):402-414. |
| Availability: |
Taylor & Francis. Available from: Taylor & Francis, Ltd. 530 Walnut Street Suite 850, Philadelphia, PA 19106. Tel: 800-354-1420; Tel: 215-625-8900; Fax: 215-207-0050; Web site: http://www.tandf.co.uk/journals |
| Peer Reviewed: |
Y |
| Page Count: |
13 |
| Publication Date: |
2024 |
| Document Type: |
Journal Articles; Reports - Research |
| Descriptors: |
Foreign Countries; Diagnostic Tests; Alzheimers Disease; Down Syndrome; Measurement Techniques; German; Adults; Dementia; Test Validity; Test Reliability; Symptoms (Individual Disorders); Age Differences; Severity (of Disability) |
| Geographic Terms: |
Germany |
| DOI: |
10.3109/13668250.2024.2317794 |
| ISSN: |
1366-8250; 1469-9532 |
| Abstract: |
Background: The CAMDEX-DS is an instrument to diagnose Alzheimer's disease (AD) in Down syndrome consisting of an informant interview and a cognitive test battery (CAMCOG-DS). Measurement properties of the German CAMDEX-DS were investigated. Method: Fifty-five adults with Down syndrome (19-58 years) participated in this observational study. "Dementia" and "Alzheimer's dementia" (Alzheimer's disease) were diagnosed clinically and operationalised CAMDEX-ICD-10 criteria were applied to evaluate criterion validity. Validity and reliability of the CAMCOG-DS were analysed. Results: Specificity of the interview was 69-93%; sensitivity 0-80% for "dementia"; and 0-20% for Alzheimer's disease. A complete CAMCOG-DS score was obtained in 85% (item difficulty 0.11-0.96). Construct validity and retest-reliability were low to moderate ([tau] = 0.04-0.79), inter-rater reliability excellent ([tau] = 0.70-0.89), internal consistency and selectivity acceptable to excellent. Conclusions: Currently, the CAMDEX-DS including the CAMCOG-DS are the outcome assessments for assessing dementia in Down syndrome with the best psychometric properties; however, revision is recommended. |
| Abstractor: |
As Provided |
| Entry Date: |
2024 |
| Accession Number: |
EJ1452717 |
| Database: |
ERIC |