| Title: |
The Impact of the COVID-19 Pandemic on Alcohol Use Disorder Symptoms: Testing Interactions with Polygenic Risk |
| Language: |
English |
| Authors: |
Kaitlin E. Bountress; Daniel Bustamante; Mohammad Ahangari; Fazil Aliev; Steven H. Aggen; Eva Lancaster; The Spit for Science Working Group; Roseann E. Peterson; Jasmin Vassileva; Danielle M. Dick; Ananda B. Amstadter |
| Source: |
Journal of American College Health. 2025 73(4):1532-1537. |
| Availability: |
Taylor & Francis. Available from: Taylor & Francis, Ltd. 530 Walnut Street Suite 850, Philadelphia, PA 19106. Tel: 800-354-1420; Tel: 215-625-8900; Fax: 215-207-0050; Web site: http://www.tandf.co.uk/journals |
| Peer Reviewed: |
Y |
| Page Count: |
6 |
| Publication Date: |
2025 |
| Sponsoring Agency: |
National Institute on Alcohol Abuse and Alcoholism (NIAAA) (DHHS/NIH); National Center for Research Resources (NCRR) (DHHS/NIH); National Center for Advancing Translational Sciences (NCATS) (DHHS/NIH), Clinical and Translational Science Awards (CTSA) Program |
| Contract Number: |
P20AA017828; R37AA011408 |
| Document Type: |
Journal Articles; Reports - Research |
| Education Level: |
Higher Education; Postsecondary Education |
| Descriptors: |
COVID-19; Pandemics; Alcohol Abuse; Symptoms (Individual Disorders); Substance Abuse; Longitudinal Studies; Genetics; Prediction; College Students; Hunger; Housing; At Risk Persons; Correlation; Measures (Individuals) |
| Geographic Terms: |
Virginia |
| DOI: |
10.1080/07448481.2024.2308255 |
| ISSN: |
0744-8481; 1940-3208 |
| Abstract: |
Objective: The purpose of this study was to test whether COVID impact interacts with genetic risk (polygenic risk score/PRS) to predict alcohol use disorder (AUD) symptoms. Method: Participants were n = 455 college students (79.6% female, 51% European Ancestry/EA, 24% African Ancestry/AFR, 25% Americas Ancestry/AMER) from a longitudinal study during the initial stage (March-May 2020) of the pandemic. Path models allowed for the examination of PRS and previously identified COVID-19 impact constructs. Results: There was a main effect of the AUD PRS on AUD symptoms within the EA group ([beta]: 0.165, p < 0.01). Additionally, food/housing insecurity was predictive in the AMER group ([beta]: 0.295, p < 0.05), and greater increases in substance use were associated with AUD symptoms for EA ([beta]: 0.459, p < 0.001) and AMER groups ([beta]: 0.468, p < 0.001). Conclusions: Greater food/housing instability and increases in substance use, as well higher scores on PRS are associated with more AUD symptoms for some ancestral groups within this college sample. |
| Abstractor: |
As Provided |
| Entry Date: |
2025 |
| Accession Number: |
EJ1473389 |
| Database: |
ERIC |