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An Introduction to Inverse Probability Weighting and Marginal Structural Models: The Case of Environmental Tobacco Exposure and Attention Deficit/Hyperactivity Disorder Behaviors

Title: An Introduction to Inverse Probability Weighting and Marginal Structural Models: The Case of Environmental Tobacco Exposure and Attention Deficit/Hyperactivity Disorder Behaviors
Language: English
Authors: Michael T. Willoughby (ORCID 0000-0002-8470-3533); Siri Warkentien; Erica N. Browne; Lisa Gatzke-Kopp; Daniel Berry
Source: Developmental Psychology. 2025 61(1):195-213.
Availability: American Psychological Association. Journals Department, 750 First Street NE, Washington, DC 20002. Tel: 800-374-2721; Tel: 202-336-5510; Fax: 202-336-5502; e-mail: order@apa.org; Web site: http://www.apa.org
Peer Reviewed: Y
Page Count: 19
Publication Date: 2025
Sponsoring Agency: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) (DHHS/NIH); Office of the Director (OD) (DHHS/NIH)
Contract Number: P01HD039667; UG3OD023332
Document Type: Journal Articles; Reports - Research
Education Level: Early Childhood Education; Elementary Education; Grade 1; Primary Education
Descriptors: Smoking; Attention Deficit Hyperactivity Disorder; Environmental Influences; Grade 1; Young Children; At Risk Persons; Family Environment; Individual Characteristics
Geographic Terms: North Carolina
DOI: 10.1037/dev0001803
ISSN: 0012-1649; 1939-0599
Abstract: Developmental scientists routinely examine how a focal predictor relates to some aspect of children's development. Although covariate adjustment is typically used to test hypotheses, propensity score-based methods, including inverse probability of treatment weighting (IPTW) and marginal structural models (MSM), can strengthen inference and answer more nuanced, developmentally relevant questions. This article provides a didactic introduction to IPTW and MSM methods and demonstrates their use for testing the impact of environmental smoke exposure (continuous treatment) from 6 to 90 months on parent-reported attention deficit hyperactivity disorder behaviors in first grade for 1,053 children (51% male, 44% Black) in the Family Life Project. We highlight differences that result both in conclusions and in the evaluation of assumptions for IPTW and MSM relative to more traditional covariate adjustment methods. Sample Stata syntax is provided.
Abstractor: As Provided
Entry Date: 2026
Accession Number: EJ1502245
Database: ERIC