| Title: |
Description of the identified case of a new porcine circovirus, PCV3, in France ; Description du premier cas d’identification d’un nouveau circovirus porcin, le PCV3, en France |
| Authors: |
Contrant, Maud; Bernard, Cécilia; Bigault, Lionel; Fablet, Christelle; Normand, Valérie; Rose, Nicolas; Blanchard, Yannick |
| Contributors: |
Laboratoire de Ploufragan-Plouzané-Niort ANSES; Agence nationale de sécurité sanitaire de l'alimentation, de l'environnement et du travail (ANSES); Porc. Spective; IFIP; INRAE |
| Source: |
54es Journées de la Recherche Porcine; https://anses.hal.science/anses-03831021; 54es Journées de la Recherche Porcine, Feb 2022, en ligne, France. Ifip, Journées de la Recherche Porcine, 54, pp.407-408, 2022, 54es Journées de la Recherche Porcine; http://www.journees-recherche-porcine.com/ |
| Publisher Information: |
HAL CCSD; Ifip |
| Publication Year: |
2022 |
| Collection: |
Archive ouverte HAL (Hyper Article en Ligne, CCSD - Centre pour la Communication Scientifique Directe) |
| Subject Terms: |
Circovirus; Pig; Identification; porc; [SDV.BA.MVSA]Life Sciences [q-bio]/Animal biology/Veterinary medicine and animal Health; [SDV.SA]Life Sciences [q-bio]/Agricultural sciences |
| Subject Geographic: |
en ligne; France |
| Description: |
International audience ; Porcine circovirus 3 (PCV3) was first identified by meta-genomics in the United States in 2015 on a farm that had recorded an increase in the mortality rate, a decrease in sow reproduction and clinical signs compatible with nephropathy dermatitis syndrome. Epidemiologically, PCV3 has gradually spread to several countries, including some in Europe, and is currently widely distributed in pigs and wild boars throughout the world. In 2019, a PCV3 infection was identified for the first time in France during suspected atypical circovirosis on a farm with post-weaning growth retardation and withering at the beginning of fattening. Histological examinations performed on 3 animals with typical clinical signs showed lymphoid depletion, lympho-histiocytic infiltration and the presence of syncytial cells that are typical lesions of circovirosis. Immuno-histochemical examination with an anti-CAP PCV2 antibody was found to be positive, but detection of the PCV2 viral genome by qPCR was negative. Qualitative and quantitative PCR of the PCV3 genome carried out on samples from fattening pigs showing signs of atypical circovirosis were found to be positive. SANGER sequencing of PCR products confirmed the presence of the PCV3 viral genome in these pigs. These results show for the first time the detection of PCV3 in the French pig herd associated with clinical manifestations of circovirosis. Research is currently underway to evaluate the real involvement of PCV3 in the various syndromes associated with its presence. ; Le circovirus porcin de type 3 (PCV3) appartient à la famille des circoviridae et au genre des circovirus. Il s'agit du quatrième membre des circovirus capable d'infecter le porc, en plus du PCV1 (Tischer et al., 1974), considéré comme non pathogène pour le porc, du PCV2, associé à un ensemble de maladies porcines dont la maladie de l’amaigrissement du porcelet (MAP), avec un impact économique très important pour l’industrie porcine (Allan and Ellis, 2000), et enfin le PCV4,identifié en Chine ... |
| Document Type: |
conference object; still image |
| Language: |
French |
| Relation: |
anses-03831021; https://anses.hal.science/anses-03831021; https://anses.hal.science/anses-03831021/document; https://anses.hal.science/anses-03831021/file/s29.pdf |
| Availability: |
https://anses.hal.science/anses-03831021; https://anses.hal.science/anses-03831021/document; https://anses.hal.science/anses-03831021/file/s29.pdf |
| Rights: |
info:eu-repo/semantics/OpenAccess |
| Accession Number: |
edsbas.10268E8C |
| Database: |
BASE |