| Title: |
Evolution of Coronary Stents: From Birth to Future Trends |
| Authors: |
Zhuo Huang; Charles Skarbek; Yulin Li; Joseph Touma; Pascal Desgranges; Romain Gallet; Jean Sénémaud |
| Source: |
Journal of Clinical Medicine ; Volume 15 ; Issue 1 ; Pages: 47 |
| Publisher Information: |
Multidisciplinary Digital Publishing Institute |
| Publication Year: |
2025 |
| Collection: |
MDPI Open Access Publishing |
| Subject Terms: |
coronary artery disease; percutaneous coronary intervention; coronary stents; stent coating; stent functionalization; personalized devices |
| Description: |
Coronary artery disease (CAD) remains one of the leading causes of mortality worldwide, affecting more than 300 million people. Over the past two decades, percutaneous coronary intervention (PCI) has become the cornerstone of CAD treatment, involving the implantation of coronary stents. This review clarifies how coronary stents emerged, evolved, and ultimately reshaped modern interventional cardiology. Beginning with balloon angioplasty and progressing through bare-metal and drug-eluting stents, we show how each advancement solved key clinical shortcomings—dramatically reducing restenosis, thrombosis, and repeat revascularization. We further review the major technological advances driving modern stent development, such as biodegradable alloys and biomimetic coatings. We also highlight the remaining challenges, including long-term stability, manufacturing complexity, and limited translational readiness. Together, these elements support our central thesis: that the historical evolution of coronary stents is fundamental to understanding present PCI practice and to guiding the next phase of device innovation. |
| Document Type: |
text |
| File Description: |
application/pdf |
| Language: |
English |
| Relation: |
Cardiology; https://dx.doi.org/10.3390/jcm15010047 |
| DOI: |
10.3390/jcm15010047 |
| Availability: |
https://doi.org/10.3390/jcm15010047 |
| Rights: |
https://creativecommons.org/licenses/by/4.0/ |
| Accession Number: |
edsbas.102B2C3F |
| Database: |
BASE |