| Title: |
Hemoglobin-to-creatinine ratio predicts one-year adverse clinical outcomes in ST-elevation myocardial infarction: retrospective and propensity score matched analysis |
| Authors: |
Spadafora, Luigi; Cacciatore, Stefano; Galli, Mattia; Collet, Carlos; Betti, Matteo; Sarto, Gianmarco; Simeone, Beatrice; Rocco, Erica; D'Ascenzo, Fabrizio; De Ferrari, Gaetano Maria; De Filippo, Ovidio; Sabouret, Pierre; Colaiori, Iginio; Carnevale, Roberto; Valenti, Valentina; Gaudio, Carlo; Zimatore, Francesca Romana; Frati, Giacomo; Versaci, Francesco; Sciarretta, Sebastiano; Biondi Zoccai, Giuseppe; Bernardi, Marco |
| Contributors: |
Spadafora, Luigi; Cacciatore, Stefano; Galli, Mattia; Collet, Carlo; Betti, Matteo; Sarto, Gianmarco; Simeone, Beatrice; Rocco, Erica; D'Ascenzo, Fabrizio; De Ferrari, Gaetano Maria; De Filippo, Ovidio; Sabouret, Pierre; Colaiori, Iginio; Carnevale, Roberto; Valenti, Valentina; Gaudio, Carlo; Zimatore, Francesca Romana; Frati, Giacomo; Versaci, Francesco; Sciarretta, Sebastiano; Biondi Zoccai, Giuseppe; Bernardi, Marco |
| Publication Year: |
2025 |
| Collection: |
Sapienza Università di Roma: CINECA IRIS |
| Subject Terms: |
STEMI; anemia; hemoglobin to creatinine ratio; myocardial infarction; renal impairment |
| Description: |
Background/Objectives: Anemia and renal impairment are key predictors of adverse outcomes in acute coronary syndromes (ACSs). The hemoglobin-to-creatinine (Hb/Cr) ratio combines these parameters into a simple index. This study aimed to evaluate its prognostic value at discharge in patients with ST-elevation myocardial infarction (STEMI). Methods: The primary endpoint was one-year all-cause mortality; secondary endpoints included major bleeding and the composite of all-cause mortality or reinfarction. Optimal Hb/Cr cut-off values were identified using Liu's method. Multivariable logistic regression and propensity score matching were used to assess associations with outcomes. Results: We analyzed 11,236 STEMI patients from the PRAISE registry with available hemoglobin and creatinine values at discharge. The optimal cut-points were 13.68 for mortality and 14.42 for secondary endpoints. Patients were stratified into low ( |
| Document Type: |
article in journal/newspaper |
| Language: |
Italian |
| Relation: |
info:eu-repo/semantics/altIdentifier/pmid/40283586; volume:14; issue:8; firstpage:1; lastpage:15; numberofpages:15; journal:JOURNAL OF CLINICAL MEDICINE; https://hdl.handle.net/11573/1753218 |
| DOI: |
10.3390/jcm14082756 |
| Availability: |
https://hdl.handle.net/11573/1753218; https://doi.org/10.3390/jcm14082756 |
| Rights: |
info:eu-repo/semantics/openAccess ; license:Creative commons ; license uri:http://creativecommons.org/licenses/by/4.0/ |
| Accession Number: |
edsbas.1198BE1B |
| Database: |
BASE |