| Title: |
The diagnostic value of the 12-Lead ECG in arrhythmogenic left ventricular cardiomyopathy |
| Authors: |
Calò, Leonardo; Crescenzi, Cinzia; Martino, Annamaria; Casella, Michela; Romeo, Fabiana; Cappelletto, Chiara; Bressi, Edoardo; Panattoni, Germana; Stolfo, Davide; Targetti, Mattia; Toso, Elisabetta; Musumeci, Maria Beatrice; Tini, Giacomo; Ciabatti, Michele; Stefanini, Matteo; Silvetti, Elisa; Stazi, Alessandra; Danza, Maria Ludovica; Rebecchi, Marco; Canestrelli, Stefano; Fedele, Elisa; Lanzillo, Chiara; Fusco, Armando; Sangiuolo, Federica Carla; Oliviero, Giada; Radesich, Cinzia; Perotto, Maria; Pieroni, Maurizio; Golia, Paolo; Mango, Ruggiero; Gasperetti, Alessio; Autore, Camillo; Merlo, Marco; de Ruvo, Ermenegildo; Russo, Antonio Dello; Olivotto, Iacopo; Sinagra, Gianfranco; Gaita, Fiorenzo |
| Contributors: |
Calò, L; Crescenzi, C; Martino, A; Casella, M; Romeo, F; Cappelletto, C; Bressi, E; Panattoni, G; Stolfo, D; Targetti, M; Toso, E; Musumeci, Mb; Tini, G; Ciabatti, M; Stefanini, M; Silvetti, E; Stazi, A; Danza, Ml; Rebecchi, M; Canestrelli, S; Fedele, E; Lanzillo, C; Fusco, A; Sangiuolo, Fc; Oliviero, G; Radesich, C; Perotto, M; Pieroni, M; Golia, P; Mango, R; Gasperetti, A; Autore, C; Merlo, M; De Ruvo, E; Russo, Ad; Olivotto, I; Sinagra, G; Gaita, F |
| Publisher Information: |
ELSEVIER |
| Publication Year: |
2023 |
| Collection: |
Universitá degli Studi di Roma "Tor Vergata": ART - Archivio Istituzionale della Ricerca |
| Subject Terms: |
sudden death; electrocardiography; desmosome; cardiomyopathy; cardiac magnetic resonance; cardiac; arrhythmogenic right ventricular cardiomyopathy; Settore MED/03; Settore MEDS-07/B - Malattie dell'apparato cardiovascolare |
| Description: |
Background: electrocardiographic (ECG) findings in arrhythmogenic left ventricular cardiomyopathy (ALVC) are limited to small case series. Objectives: this study aimed to analyze the ECG characteristics of ALVC patients and to correlate ECG with cardiac magnetic resonance and genotype data. methods: we reviewed data of 54 consecutive ALVC patients (32 men, age 39 +/- 15 years) and compared them with 84 healthy controls with normal cardiac magnetic resonance. Results: T-wave inversion was often noted (57.4%), particularly in the inferior and lateral leads. Low QRS voltages in limb leads were observed in 22.2% of patients. the following novel ECG findings were identified: left posterior fascicular block (LPFB) (20.4%), pathological Q waves (33.3%), and a prominent R-wave in V-1 with a R/S ratio >= 0.5 (24.1%). the QRS voltages were lower in ALVC compared with controls, particularly in lead I and II. at receiver-operating characteristic analysis, the sum of the R-wave in I to II |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| Relation: |
info:eu-repo/semantics/altIdentifier/pmid/37768253; info:eu-repo/semantics/altIdentifier/wos/WOS:001147357600001; volume:9; issue:12; firstpage:2615; lastpage:2627; numberofpages:13; journal:JACC. CLINICAL ELECTROPHYSIOLOGY; https://hdl.handle.net/2108/369503 |
| DOI: |
10.1016/j.jacep.2023.08.020 |
| Availability: |
https://hdl.handle.net/2108/369503; https://doi.org/10.1016/j.jacep.2023.08.020 |
| Rights: |
info:eu-repo/semantics/restrictedAccess ; license:Copyright dell'editore ; license uri:iris.publisher |
| Accession Number: |
edsbas.12211A61 |
| Database: |
BASE |