| Title: |
Genome-wide association study reveals new insights into the heritability and genetic correlates of developmental dyslexia |
| Authors: |
Gialluisi, A; Andlauer, TFM; Mirza-Schreiber, N; Moll, K; Becker, J; Hoffmann, P; Ludwig, KU; Czamara, D; Pourcain, BS; Honbolygó, F; Tóth, D; Csépe, V; Huguet, G; Chaix, Y; Iannuzzi, S; Demonet, J-F; Morris, AP; Hulslander, J; Willcutt, EG; DeFries, JC; Olson, RK; Smith, SD; Pennington, BF; Vaessen, A; Maurer, U; Lyytinen, H; Peyrard-Janvid, M; Leppänen, PHT; Brandeis, D; Bonte, M; Stein, JF; Talcott, JB; Fauchereau, F; Wilcke, A; Kirsten, H; Müller, B; Francks, C; Bourgeron, T; Monaco, AP; Ramus, F; Landerl, K; Kere, J; Scerri, TS; Paracchini, S; Fisher, SE; Schumacher, J; Nöthen, MM; Müller-Myhsok, B; Schulte-Körne, G |
| Publisher Information: |
Springer Nature [academic journals on nature.com] |
| Publication Year: |
2026 |
| Collection: |
Oxford University Research Archive (ORA) |
| Description: |
Background: Mental health has a low early mortality rate, but contributes the most to disability and recurrence is an indicator of successful treatment of mental disorders, including bipolar. Bipolar relapse is caused by many factors or high-risk situations. Purpose: The purpose of this study was to analyze the determinants of bipolar relapse from a cognitive-behavioral model of relapse. Method: This research was conducted at Islamic Hospital of Madinah Tulungagung used a correlational design with a cross sectional approach to 108 respondents who were taken using a simple random sampling technique. The exogenous variables were genetics, age of onset, gender, occupation, marriage, family support, social capital, stigma, self-efficacy, motivation, medication adherence and the endogenous variable was bipolar relapse, using a questionnaire and analyzed path analysis. Results: Genetics, occupation, social capital, self-efficacy, motivation, medication adherence, community stigma and family support have a direct effect on bipolar relapse with a p-value |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| DOI: |
10.1038/s41380-020-00898-x |
| Availability: |
https://doi.org/10.1038/s41380-020-00898-x; https://ora.ox.ac.uk/objects/uuid:aaeb63b8-3905-42b5-ad18-b15be987fc44 |
| Rights: |
info:eu-repo/semantics/openAccess ; CC Attribution (CC BY) |
| Accession Number: |
edsbas.1264FBDA |
| Database: |
BASE |