| Title: |
Development and association of new metrics of dose and image quality for comparing and optimizing protocols in CT imaging |
| Authors: |
Simon, Anne-Catherine; Othman, Nadia; Boissonnat, Guillaume; Lazaro, Delphine; García Hernández, Juan-Carlos; Berteloot, L.; Grevent, D.; Habib Geryes, Bouchra; Gempp, S.; Desrousseaux, J.; Bigand, E.; Benkreira, M.; Vincent, M.; Capdeville, S.; Nigoul, J.M.; Farman, B.; Garnier, E.; Nomikossoff, N. |
| Contributors: |
Laboratoire Modélisation et Simulation de Systèmes (CEA, LIST) (LM2S (CEA, LIST)); Département Métrologie Instrumentation & Information (CEA, LIST) (DM2I (CEA, LIST)); Laboratoire d'Intégration des Systèmes et des Technologies (LIST (CEA)); Direction de Recherche Technologique (CEA) (DRT (CEA)); Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Direction de Recherche Technologique (CEA) (DRT (CEA)); Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Laboratoire d'Intégration des Systèmes et des Technologies (LIST (CEA)); Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay; Hôpital Necker - Enfants Malades AP-HP; Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP); Assistance Publique - Hôpitaux de Marseille (APHM); Société Française de Physique Médicale |
| Source: |
Abstracts of the 58èmes Journées Scientifiques de la Société Française de Physique MédicalePhysica Medica, Volume 68, Supplement 1, Pages 1-54 (December 2019) ; 58es Journées Scientifiques de la Société Française de Physique Médicale ; https://cea.hal.science/cea-04558838 ; 58es Journées Scientifiques de la Société Française de Physique Médicale, Société Française de Physique Médicale, Jun 2019, Angers, France. pp.35-36, ⟨10.1016/j.ejmp.2019.09.137⟩ ; https://www.sciencedirect.com/journal/physica-medica/vol/68/suppl/S1 |
| Publisher Information: |
CCSD; Physica Medica |
| Publication Year: |
2019 |
| Subject Terms: |
Non Pre-Whitening Eyefilter; detectability index; signal processing; lesion detection; discrimination; phantom; irradiation; reconstruction conditions; clinical study; dose estimation; Monte Carlo; particle transport; PENELOPE; anthropomorphic phantom; CTDI; ionization chamber; Optically Stimulated Luminescence dosimeter; OSL; dosimeter; dose level; standardization; total imaging collective dose; ionizing radiation; metrology; medical physics; Computed Tomography; dosimetry; Medical imaging; CT imaging; Tomography |
| Subject Geographic: |
Angers; France |
| Description: |
International audience ; Introduction. Nowadays, though Computed Tomography (CT) examinations only correspond to a small portion of medical imaging procedures (typically 10 % in France in 2012), they are credited with about 70 % of the total imaging collective dose. Reducing the dose due to CT examinations is therefore a major issue worldwide but cannot be achieved at the expense of the image quality (IQ) needed to ensure a correct diagnosis.Therefore, CT imaging needs to be described simultaneously using reliable metrics for delivered dose and IQ. However, such metrics are still lacking, especially for IQ. In this study, we developed and combined new metrics of IQ and patient dose in order to compare CT protocols.Methods. For IQ evaluation, the mathematical model observer (MO) Non Pre-Whitening Eyefilter (Burgess, 1994) was implemented to estimate a detectability index linked to clinical tasks such as lesion detection or discrimination. The index was calculated on CT images of a home-made dedicated phantom acquired for various irradiation and reconstruction conditions. It was then validated in the framework of a clinical study involving a dozen of experienced radiologists, on the large set on images presented in two Alternative Forced Choice (2-AFC) experiments for both tasks. After rescaling on their responses, the MO provided a Percentage of Correct answers (PC) depending on the acquisition parameters, the task and the insert size.For dose estimation, a complete Monte Carlo model of the GE Discovery CT750 HD scanner was developed with the PENELOPE code. All the components of the scanner were estimated by physical measurements. The modelling was validated with measurements in CTDI and anthropomorphic phantoms using ion chambers and Optically Stimulated Luminescence dosimeters. Once validated, dose levels were calculated in the home-made torso-shaped phantom for every acquisition parameter used in the clinical study. Curves linking PC values calculated by the MO with the simulated dose in the phantom were then ... |
| Document Type: |
conference object |
| Language: |
English |
| DOI: |
10.1016/j.ejmp.2019.09.137 |
| Availability: |
https://cea.hal.science/cea-04558838; https://cea.hal.science/cea-04558838v1/document; https://cea.hal.science/cea-04558838v1/file/Presentation_ACSimon_2019-06-06%20-%20SFPM%20-%20Optimisation%20protocoles_pour_diffusion_CEA_DOSEO.pdf; https://doi.org/10.1016/j.ejmp.2019.09.137 |
| Rights: |
info:eu-repo/semantics/OpenAccess |
| Accession Number: |
edsbas.136A0DEF |
| Database: |
BASE |