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Longitudinal associations between fruit and vegetable intakes and depressive symptoms in middle-aged and older adults from four international twin cohorts

Title: Longitudinal associations between fruit and vegetable intakes and depressive symptoms in middle-aged and older adults from four international twin cohorts
Authors: Matison, AP; Thalamuthu, A; Flood, VM; Catts, VS; Christensen, K; Nygaard, M; Pedersen, NL; Sachdev, PS; Reppermund, S; Mather, KA
Source: urn:ISSN:2045-2322 ; Scientific Reports, 14, 1, 29711
Publisher Information: Springer Nature
Publication Year: 2024
Collection: UNSW Sydney (The University of New South Wales): UNSWorks
Subject Terms: 32 Biomedical and Clinical Sciences; 4206 Public Health; 42 Health Sciences; 3210 Nutrition and Dietetics; Depression; Brain Disorders; Mental Illness; Mental Health; Aging; Humans; Fruit; Middle Aged; Vegetables; Aged; Female; Male; Longitudinal Studies; 80 and over; Australia; Sweden; Diet; Denmark; United States; Depressive symptoms; Longitudinal study; Twin study; Interplay of Genes and Environment across Multiple Studies (IGEMS) consortium; anzsrc-for: 32 Biomedical and Clinical Sciences; anzsrc-for: 4206 Public Health; anzsrc-for: 42 Health Sciences
Description: Beneficial associations between higher fruit and vegetable intakes and risk of depression appear to exist but few studies have focused on adults aged 45 + years and the potential that associations are due to residual confounding has not been tested. This longitudinal study of twins (n = 3483, age 45–90 years) from Australia, Denmark, Sweden and USA, assessed the associations between baseline fruit/vegetable intake and depressive symptoms over 5–11 years using linear mixed effects models. Intakes from food frequency questionnaires were trichotomized. Depressive symptoms were assessed using validated measures. The co-twin method was used to examine familial confounding. Compared with low intakes, both high fruit and high vegetable intakes were associated with lower depressive symptoms (fruit: β -.007 [95%CI −.014, < −.001], p =.040; vegetables: β −.006 [95%CI -.011, -.002], p =.002); whereas only moderate vegetable intakes, were associated with lower depressive symptoms (vegetables: β −.005 [95%CI −.009, −.001], p =.014). No familial confounding was found for vegetables, while the results for fruit were inconclusive, likely due to smaller sample size and the marginal significance of the main result. Higher fruit and vegetable intakes may protect against depressive symptoms, presenting another argument for increasing intakes in adults aged 45 + years.
Document Type: article in journal/newspaper
File Description: application/pdf
Language: unknown
Relation: https://hdl.handle.net/1959.4/105172
DOI: 10.1038/s41598-024-79963-2
Availability: https://hdl.handle.net/1959.4/105172; https://unsworks.unsw.edu.au/bitstreams/19d37ea5-0dd9-41c1-a14b-b3f66d458be3/download; https://doi.org/10.1038/s41598-024-79963-2
Rights: open access ; https://purl.org/coar/access_right/c_abf2 ; CC BY-NC-ND ; https://creativecommons.org/licenses/by-nc-nd/4.0/ ; free_to_read
Accession Number: edsbas.15602D4D
Database: BASE