| Title: |
[2]Catenane Synthesis via Covalent Templating |
| Authors: |
Pilon, Simone; Ingemann Jørgensen, Steen; van Maarseveen, Jan H. |
| Contributors: |
Nederlandse Organisatie voor Wetenschappelijk Onderzoek |
| Source: |
Chemistry – A European Journal ; volume 27, issue 7, page 2310-2314 ; ISSN 0947-6539 1521-3765 |
| Publisher Information: |
Wiley |
| Publication Year: |
2021 |
| Collection: |
Wiley Online Library (Open Access Articles via Crossref) |
| Description: |
After earlier unsuccessful attempts, this work reports the application of covalent templating for the synthesis of mechanically interlocked molecules (MiMs) bearing no supramolecular recognition sites. Two linear strands were covalently connected in a perpendicular fashion by a central ketal linkage. After subsequent attachment of the first strand to a template via temporary benzylic linkages, the second was linked to the template in a backfolding macrocyclization. The resulting pseudo[1]rotaxane structure was successfully converted to a [2]catenane via a second macrocyclization and cleavage of the ketal and temporary linkages. |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| DOI: |
10.1002/chem.202004925 |
| Availability: |
https://doi.org/10.1002/chem.202004925; https://onlinelibrary.wiley.com/doi/pdf/10.1002/chem.202004925; https://onlinelibrary.wiley.com/doi/full-xml/10.1002/chem.202004925 |
| Rights: |
http://creativecommons.org/licenses/by/4.0/ |
| Accession Number: |
edsbas.15D46B41 |
| Database: |
BASE |