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Higher circulating FGF21, lower protein intake, and lower muscle mass:Associations with a higher risk of mortality

Title: Higher circulating FGF21, lower protein intake, and lower muscle mass:Associations with a higher risk of mortality
Authors: Post, Adrian; Dam, Wendy A; Groothof, Dion; Franssen, Casper F M; Bakker, Stephan J L; Dullaart, Robin P F
Source: Post, A, Dam, W A, Groothof, D, Franssen, C F M, Bakker, S J L & Dullaart, R P F 2025, 'Higher circulating FGF21, lower protein intake, and lower muscle mass : Associations with a higher risk of mortality', Journal of Internal Medicine, vol. 298, no. 1, pp. 2-15. https://doi.org/10.1111/joim.20099
Publication Year: 2025
Collection: University of Groningen research database
Description: BACKGROUND AND OBJECTIVES: This population-based study explores associations of fibroblast growth factor 21 (FGF21), a key modulator of processes linked to protein metabolism, with protein intake and muscle mass, and their relationships with all-cause mortality. METHODS: In 6395 participants (mean age 54 years; 50% women), circulating FGF21 (immunoassay), protein intake (Maroni equation using 24-h urinary urea excretion; low intake defined as
Document Type: article in journal/newspaper
File Description: application/pdf
Language: English
ISSN: 0954-6820
Relation: info:eu-repo/semantics/altIdentifier/pmid/40390366; info:eu-repo/semantics/altIdentifier/hdl/https://hdl.handle.net/11370/1eb0401b-0896-4faf-8844-74671fadc896; info:eu-repo/semantics/altIdentifier/pissn/0954-6820
DOI: 10.1111/joim.20099
Availability: https://hdl.handle.net/11370/1eb0401b-0896-4faf-8844-74671fadc896; https://research.rug.nl/en/publications/1eb0401b-0896-4faf-8844-74671fadc896; https://doi.org/10.1111/joim.20099; https://pure.rug.nl/ws/files/1390873389/Journal_of_Internal_Medicine_-_2025_-_Post_-_Higher_circulating_FGF21_lower_protein_intake_and_lower_muscle_mass_.pdf
Rights: info:eu-repo/semantics/openAccess ; http://creativecommons.org/licenses/by/4.0/
Accession Number: edsbas.16A34219
Database: BASE