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Health impacts of e-cigarette and traditional tobacco use in Shanghai male railway workers: A population-based retrospective cohort study

Title: Health impacts of e-cigarette and traditional tobacco use in Shanghai male railway workers: A population-based retrospective cohort study
Authors: Lishun Xiao *+; Natasha M. Weah *+; Yuan Chen; Jensen G. Weedor; Wenhong Wang; Lin Jiang; Xiaona Cong; Yansu Chen
Source: Tobacco Induced Diseases, Vol 23, Iss October, Pp 1-15 (2025)
Publisher Information: European Publishing
Publication Year: 2025
Collection: Directory of Open Access Journals: DOAJ Articles
Subject Terms: health indicators; electronic cigarettes; dual users; traditional tobacco; accumulated smoking years; Diseases of the respiratory system; RC705-779; Neoplasms. Tumors. Oncology. Including cancer and carcinogens; RC254-282
Description: Introduction The health implications of electronic cigarette (e-cigarette) use remain uncertain despite their increasing global prevalence. This study evaluates the health hazards of e-cigarettes on railway workers by comparing the differences in clinical and biochemical health indicators resulting from exposure to different smoking methods. Methods Using a retrospective cohort design, this study analyzed 7719 routine physical examinations and clinical health records from male railway workers in Shanghai (March 2022). Participants were stratified into four smoking subgroups: non-users, e-cigarette users, cigarette smokers, and dual users (concurrent e-cigarette and cigarette use). A multinomial logistic regression analysis evaluated the potential health impacts associated with each type of cigarette use, while a linear regression analyzed the impact of accumulated smoking years on these health indicators. Results E-cigarette use was associated with increased odds of elevated systolic blood pressure (AOR=1.12; 95% CI: 1.01–1.24; AOR=1.18; 95% CI: 1.06–1.31) and heart rate (AOR=1.18; 95% CI: 1.06–1.33) per 10-unit increase, as well as reduced urine pH (AOR=0.64; 95% CI: 0.52–0.80; AOR=0.70; 95% CI: 0.56– 0.88) compared to non-users and cigarette smokers. Compared to cigarette use, e-cigarette use was associated with higher hemoglobin levels (AOR=1.22; 95% CI: 1.05–1.42) and increased aspartate aminotransferase levels for every 10-unit increment (AOR=1.23; 95% CI: 1.01–1.51). Furthermore, relative to non-users, e-cigarette users showed higher levels of white blood cells and carcinoembryonic antigen, with the largest effect sizes observed among e-cigarette users compared to other subgroups. In addition, the number of accumulated smoking years significantly impacted clinical and biochemical health indicators in both cigarette and e-cigarette users. Conclusions E-cigarette use was associated with adverse alterations in several clinical and biochemical health indicators, some of which were comparable to or more ...
Document Type: article in journal/newspaper
Language: English
Relation: https://www.tobaccoinduceddiseases.org/Health-impacts-of-e-cigarette-and-traditional-tobacco-use-in-Shanghai-male-railway,209146,0,2.html; https://doaj.org/toc/1617-9625; https://doaj.org/article/445786f1e1b04d01816d684f074052a1
DOI: 10.18332/tid/209146
Availability: https://doi.org/10.18332/tid/209146; https://doaj.org/article/445786f1e1b04d01816d684f074052a1
Accession Number: edsbas.1762ED24
Database: BASE