| Title: |
Does progesterone have protective effects on ovarian ischemia-reperfusion injury? |
| Authors: |
Başer, Banu Güleç; Taşkın, Mine İslimye; Adalı, Ertan; Öztürk, Emine; Hısmıoğulları, Adnan Adil; Yay, Arzu |
| Publisher Information: |
Cihat Ünlü |
| Publication Year: |
2026 |
| Collection: |
Balıkesir University Institutional Repository (DSpace@Balıkesir) |
| Subject Terms: |
Ischemia-Reperfusion; NGAL; Progesterone |
| Description: |
Objective: The aim of the present study was to evaluate the effects of progesterone (PG) against ovarian ischemia-reperfusion (I/R) injury through the evaluation of biochemical and histopathologic parameters. Material and Methods: Twenty-one female Wistar albino rats were divided into three groups. Group 1: Sham; group 2: I/R; group 3: I/R+PG (8 mg/kg). PG was administered intraperitoneally to the rats in group 3, 30 minutes before a detorsion operation. Ovarian I/R injury was evaluated in serum and tissue by using biochemical parameters including malondialdehyde (MDA), total antioxidant status (TAS), total oxidant status (TOS), oxidative stress index, neutrophil gelatinase-associated lipocalin (NGAL) and immunofluorescence staining by using a terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling (TUNEL) assay. Results: Serum and tissue TOS levels were significantly lower in group 3 than in group 2. Tissue TAS levels were higher in group 3 than in group 2 (p |
| Document Type: |
article in journal/newspaper |
| File Description: |
application/pdf |
| Language: |
English |
| ISSN: |
13090399 |
| Relation: |
Journal of the Turkish-German Gynecological Association; Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı; https://doi.org/10.4274/jtgga.2017.0047; https://hdl.handle.net/20.500.12462/22744; 19; 87; 93; 386298 |
| DOI: |
10.4274/jtgga.2017.0047 |
| Availability: |
https://hdl.handle.net/20.500.12462/22744; https://doi.org/10.4274/jtgga.2017.0047 |
| Rights: |
info:eu-repo/semantics/openAccess |
| Accession Number: |
edsbas.178DD2C1 |
| Database: |
BASE |