| Title: |
Adiposity and risk of decline in glomerular filtration rate: Meta-analysis of individual participant data in a global consortium |
| Authors: |
Chang, AR; Grams, ME; Ballew, SH; Bilo, H; Correa, A; Evans, M; Gutierrez, OM; Hosseinpanah, F; Iseki, K; Kenealy, T; Klein, B; Kronenberg, F; Lee, BJ; Li, Y; Miura, K; Navaneethan, SD; Roderick, PJ; Valdivielso, JM; Visseren, FLJ; Zhang, L; Gansevoort, RT; Hallan, SI; Levey, AS; Matsushita, K; Shalev, V; Woodward, M; Chalmers, John; Perkovic, Vlado |
| Source: |
urn:ISSN:0959-8146 ; urn:ISSN:1756-1833 ; BMJ Online, 364, k5301 |
| Publisher Information: |
BMJ |
| Publication Year: |
2019 |
| Collection: |
UNSW Sydney (The University of New South Wales): UNSWorks |
| Subject Terms: |
4202 Epidemiology; 42 Health Sciences; Cardiovascular; Kidney Disease; Nutrition; Aging; Obesity; 2.4 Surveillance and distribution; Renal and urogenital; 3 Good Health and Well Being; Adiposity; Adult; Aged; 80 and over; Body Height; Body Mass Index; Cohort Studies; Female; Glomerular Filtration Rate; Humans; Kidney Failure; Chronic; Male; Middle Aged; Mortality; Risk Factors; Waist Circumference; CKD Prognosis Consortium (CKD-PC); anzsrc-for: 4202 Epidemiology; anzsrc-for: 42 Health Sciences |
| Description: |
Objective To evaluate the associations between adiposity measures (body mass index, waist circumference, and waist-to-height ratio) with decline in glomerular filtration rate (GFR) and with all cause mortality. Design Individual participant data meta-analysis. Setting Cohorts from 40 countries with data collected between 1970 and 2017. Participants Adults in 39 general population cohorts (n=5 459 014), of which 21 (n=594 496) had data on waist circumference; six cohorts with high cardiovascular risk (n=84 417); and 18 cohorts with chronic kidney disease (n=91 607). Main outcome measures GFR decline (estimated GFR decline ≥40%, initiation of kidney replacement therapy or estimated GFR |
| Document Type: |
article in journal/newspaper |
| File Description: |
application/pdf |
| Language: |
unknown |
| Relation: |
https://hdl.handle.net/1959.4/unsworks_67136; https://doi.org/10.1136/bmj.k5301 |
| DOI: |
10.1136/bmj.k5301 |
| Availability: |
https://hdl.handle.net/1959.4/unsworks_67136; https://unsworks.unsw.edu.au/bitstreams/6875a891-ee15-4194-91c5-3ac0dd536b11/download; https://doi.org/10.1136/bmj.k5301 |
| Rights: |
open access ; https://purl.org/coar/access_right/c_abf2 ; CC BY-NC ; https://creativecommons.org/licenses/by-nc/4.0/ ; free_to_read |
| Accession Number: |
edsbas.17933EC4 |
| Database: |
BASE |