Validation of the Zwolle Risk Score in STEMI Patients Undergoing Primary PCI: Insights from the ISCAS-STEMI COVID-19 Registry
| Title: | Validation of the Zwolle Risk Score in STEMI Patients Undergoing Primary PCI: Insights from the ISCAS-STEMI COVID-19 Registry |
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| Authors: | De Luca, Giuseppe; Algowhary, Magdy; Uguz, Berat; C. Oliveira, Dinaldo; Ganyukov, Vladimir; Zimbakov, Zan; Cercek, Miha; Jensen, Lisette Okkels; Huan LOH, Poay; Calmac, Lucian; Roura i Ferrer, Gerard; Quadros, Alexandre; Malewski, Marek; Di Uccio, Fortunato Scotto; Von Birgelen, Clemens; Versaci, Francesco; ten Berg, Jurrien; Casella, Gianni; Wong Sung Lung, Aaron; Kala, Petr; Díez Gil, José Luis; Carillo, Xavier; T Dirksen, Maurits; Manuel Becerra-Munoz, Victor; Kang-yin Lee, Michael; Arifa Juzar, Dafsah; de Moura Joaquim, Rodrigo; Paladino, Roberto; Miličić, Davor; Davlouros, Periklis; Bakraceski, Nikola; Zilio, Filippo; Donazzan, Luca; Kraaijeveld, Adriaan; Galasso, Gennaro; Arpad, Lux; Marinucci, Lucia; Guiducci, Vincenzo; Menichelli, Maurizio; Scoccia, Alessandra; Hatice Yamac, Aylin; Ugur Mert, Kadir; flores rios, Xacobe; Kovarnik, Tomas; Kidawa, Michal; Moreu, Jose; Vincent, Flavien; Fabris, Enrico; Lozano Martínez-Luengas, Inigo; Boccalatte, Marco; Bosa Ojeda, Francisco; Arellano-Serrano, Carlos; Caiazzo, Gianluca; Cirrincione, Giuseppe; Kao, Hsien-Li; Sanchis Fores, Juan; Vignali, Luigi; Pereira, Hélder; Manzo-Silbermann, Stephane; Ordonez, Santiago; Arat Ozkan, Alev; Scheller, Bruno; Lehtola, Heidi; Teles, Rui; Mantis, Christos; Antti, Ylitalo; Brum Silveira, Joao Antonio; Zoni, Rodrigo; Bessonov, Ivan; Savonitto, Stefano; Kochiadakis, George; Alexopulos, Dimitrios; E Uribe, Carlos; Kanakakis, John; Faurie, Benjamin; Gabrielli, Gabriele; Gutierrez Barrios, Alexandro; Bachini, Jaun Pablo; Rocha, Alex; Chor-Cheung Tam, Frankie; Rodriguez, Alfredo; Lukito, Antonia Anna; Saint Joy, Veauthyelau; Pessah, Gustavo; Cortese, Giuliana; Parodi, Guido; Burgadha, Mohammed Abed; Kedhi, Elvin; Lamelas, Pablo; Suryapranata, Harry; Nardin, Matteo; Verdoia, Monica |
| Contributors: | De Luca, Giuseppe; Algowhary, Magdy; Uguz, Berat; C. Oliveira, Dinaldo; Ganyukov, Vladimir; Zimbakov, Zan; Cercek, Miha; Jensen, Lisette Okkel; Huan Loh, Poay; Calmac, Lucian; Roura I Ferrer, Gerard; Quadros, Alexandre; Malewski, Marek; Di Uccio, Fortunato Scotto; Von Birgelen, Clemen; Versaci, Francesco; Ten Berg, Jurrien; Casella, Gianni; Wong Sung Lung, Aaron; Kala, Petr; Díez Gil, José Lui; Carillo, Xavier; T Dirksen, Maurit; Manuel Becerra-Munoz, Victor; Kang-yin Lee, Michael; Arifa Juzar, Dafsah; De Moura Joaquim, Rodrigo; Paladino, Roberto; Miličić, Davor; Davlouros, Perikli; Bakraceski, Nikola; Zilio, Filippo; Donazzan, Luca; Kraaijeveld, Adriaan; Galasso, Gennaro; Arpad, Lux; Marinucci, Lucia; Guiducci, Vincenzo; Menichelli, Maurizio; Scoccia, Alessandra; Hatice Yamac, Aylin; Ugur Mert, Kadir; Flores Rios, Xacobe; Kovarnik, Toma; Kidawa, Michal; Moreu, Jose; Vincent, Flavien; Fabris, Enrico; Lozano Martínez-Luengas, Inigo; Boccalatte, Marco; Bosa Ojeda, Francisco; Arellano-Serrano, Carlo; Caiazzo, Gianluca; Cirrincione, Giuseppe; Kao, Hsien-Li; Sanchis Fores, Juan; Vignali, Luigi; Pereira, Hélder; Manzo-Silbermann, Stephane; Ordonez, Santiago; Arat Ozkan, Alev; Scheller, Bruno; Lehtola, Heidi; Teles, Rui; Mantis, Christo; Antti, Ylitalo; Brum Silveira, Joao Antonio; Zoni, Rodrigo; Bessonov, Ivan; Savonitto, Stefano; Kochiadakis, George; Alexopulos, Dimitrio; E Uribe, Carlo; Kanakakis, John; Faurie, Benjamin; Gabrielli, Gabriele; Gutierrez Barrios, Alexandro; Bachini, Jaun Pablo; Rocha, Alex; Chor-Cheung Tam, Frankie; Rodriguez, Alfredo; Lukito, Antonia Anna; Saint Joy, Veauthyelau; Pessah, Gustavo; Cortese, Giuliana; Parodi, Guido; Burgadha, Mohammed Abed; Kedhi, Elvin; Lamelas, Pablo; Suryapranata, Harry; Nardin, Matteo; Verdoia, Monica |
| Publisher Information: | Bentham Science Publishers |
| Publication Year: | 2026 |
| Collection: | Padua Research Archive (IRIS - Università degli Studi di Padova) |
| Subject Terms: | COVID-19 registry; mechanical reperfusion; pandemic; STEMI patient; Zwolle Risk Score |
| Description: | Background: Several scores have been developed to facilitate risk stratification and early discharge following primary angioplasty, particularly the Zwolle Risk Score (ZRS). However, validation in large-sized studies is still lacking. Therefore, the aim of the current study was to validate the use of the ZRS in a contemporary global population, including patients who were treated during the SARS-CoV-2 pandemic and enrolled in a large intercontinental observational study. Methods: The ISACS-STEMI COVID-19 is a large-scale retrospective multicenter registry involving primary PCI centers from Europe, Latin America, South-East Asia, and NorthAfrica, including patients treated from March 1st until June 30th, in 2019 and 2020]. ZRS was calculated for each patient. The patients were additionally categorized according to the following values of the ZRS [= 10]. Our study outcomes were in-hospital and 30-day mortality. The discriminatory capacity of the ZRS was assessed by the area under the ROC curve [c statistic] as an index of model performance. Results: Our population is represented by 16084 STEMI patients undergoing mechanical reperfusion enrolled in 109 centers. The score showed a very good performance in the predicting mortality both in-hospital [AUC=0.83 [0.82-0.85], p |
| Document Type: | article in journal/newspaper |
| Language: | English |
| Relation: | info:eu-repo/semantics/altIdentifier/pmid/40247796; info:eu-repo/semantics/altIdentifier/wos/WOS:001484216500001; volume:24; issue:1; firstpage:68; lastpage:75; numberofpages:8; journal:CURRENT VASCULAR PHARMACOLOGY; https://hdl.handle.net/11577/3581667 |
| DOI: | 10.2174/0115701611335913250408214530 |
| Availability: | https://hdl.handle.net/11577/3581667; https://doi.org/10.2174/0115701611335913250408214530 |
| Accession Number: | edsbas.17A14A3F |
| Database: | BASE |