| Title: |
Exploration of chronic kidney disease prevalence estimates using new measures of kidney function in the health survey for England |
| Authors: |
Fraser, SD; Aitken, G; Taal, MW; Mindell, JS; Moon, G; Day, J; O'Donoghue, D; Roderick, PJ |
| Source: |
PLoS One , 10 (2) , Article e0118676. (2015) |
| Publication Year: |
2015 |
| Collection: |
University College London: UCL Discovery |
| Description: |
Chronic kidney disease (CKD) diagnosis relies on glomerular filtration rate (eGFR) estimation, traditionally using the creatinine-based Modification of Diet in Renal Disease (MDRD) equation. The Chronic Kidney Disease Epidemiology Collaboration (CKDEPI) equation performs better in estimating eGFR and predicting mortality and CKD progression risk. Cystatin C is an alternative glomerular filtration marker less influenced by muscle mass. CKD risk stratification is improved by combining creatinine eGFR with cystatin C and urinary albumin to creatinine ratio (uACR). We aimed to identify the impact of introducing CKDEPI and cystatin C on the estimated prevalence and risk stratification of CKD in England and to describe prevalence and associations of cystatin C. |
| Document Type: |
article in journal/newspaper |
| File Description: |
text |
| Language: |
English |
| Relation: |
https://discovery.ucl.ac.uk/id/eprint/1464642/1/Mindell_Exploration%20of%20chronic%20kidney%20disease%20prevalence%20estimates%20using%20new%20measures%20of%20kidney%20function%20in%20the%20health%20survey%20for%20England.pdf; https://discovery.ucl.ac.uk/id/eprint/1464642/ |
| Availability: |
https://discovery.ucl.ac.uk/id/eprint/1464642/1/Mindell_Exploration%20of%20chronic%20kidney%20disease%20prevalence%20estimates%20using%20new%20measures%20of%20kidney%20function%20in%20the%20health%20survey%20for%20England.pdf; https://discovery.ucl.ac.uk/id/eprint/1464642/ |
| Rights: |
open |
| Accession Number: |
edsbas.19782D15 |
| Database: |
BASE |