| Title: |
Can a Shorter Dwell Time Reduce Infective Complications Associated with the Use of Umbilical Catheters? |
| Authors: |
Buttera M.; Corso L.; Casadei L.; Valenza C.; Sforza F.; Candia F.; Miselli F.; Baraldi C.; Lugli L.; Berardi A.; Iughetti L. |
| Contributors: |
Buttera, M.; Corso, L.; Casadei, L.; Valenza, C.; Sforza, F.; Candia, F.; Miselli, F.; Baraldi, C.; Lugli, L.; Berardi, A.; Iughetti, L. |
| Publication Year: |
2024 |
| Collection: |
Archivio della ricerca dell'Università di Modena e Reggio Emilia (Unimore: IRIS) |
| Subject Terms: |
CLABSI; UVC; central catheter; neonate; newborn; umbilical catheters |
| Description: |
Background: Umbilical venous catheters (UVCs) are the standard of care in neonatal intensive care units (NICUs) to administer fluids, parenteral nutrition and medications, although complications may occur, including central line-associated blood stream infections (CLABSIs). However, the dwell time to reduce CLABSI risk remains an open issue. Methods: We performed a single-center retrospective study of newborns hospitalized in the Modena NICU with at least one UVC inserted over a 6-year period (period 1: January 2011-December 2013; period 2: January 2019-December 2021). We selected a non-consecutive 6-year period to emphasize the differences in UVC management practices that have occurred over time in our NICU. The UVC dwell time and catheter-related complications during the first 4 weeks of life were examined. Results: The UVC dwell time was shorter in period 2 (median 4 days vs. 5 days, p < 0.00001). Between the two periods, the incidence of CLABSIs remained unchanged (p = 0.5425). However, in period 2, there was an increased need for peripherally inserted central catheters (PICCs) after UVC removal, with a rise in PICC infections after UVC removal (p = 0.0239). Conclusions: In our NICU, shortening UVC dwell time from 5 to 4 days did not decrease the UVC-related complications. Instead, the earlier removal of UVCs led to a higher number of PICCs inserted, possibly increasing the overall infectious risk. |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| Relation: |
info:eu-repo/semantics/altIdentifier/pmid/39452254; info:eu-repo/semantics/altIdentifier/wos/WOS:001343493500001; volume:13; issue:10; firstpage:1; lastpage:8; journal:ANTIBIOTICS; https://hdl.handle.net/11380/1363546 |
| DOI: |
10.3390/antibiotics13100988 |
| Availability: |
https://hdl.handle.net/11380/1363546; https://doi.org/10.3390/antibiotics13100988 |
| Rights: |
info:eu-repo/semantics/openAccess ; license:[IR] creative-commons ; license uri:http://creativecommons.org/licenses/by/4.0/ |
| Accession Number: |
edsbas.19A6922 |
| Database: |
BASE |