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Initiation of continuous renal replacement therapy versus intermittent hemodialysis in critically ill patients with severe acute kidney injury: a secondary analysis of STARRT-AKI trial

Title:	Initiation of continuous renal replacement therapy versus intermittent hemodialysis in critically ill patients with severe acute kidney injury: a secondary analysis of STARRT-AKI trial
Authors:	Wald, Ron; Gaudry, Stephane; da Costa, Bruno R.; Adhikari, Neill K. J.; Bellomo, Rinaldo; Du, Bin; Gallagher, Martin P.; Hoste, Eric A.; Lamontagne, François; Joannidis, Michael; Liu, Kathleen D.; McAuley, Daniel F.; McGuinness, Shay P.; Nichol, Alistair D.; Ostermann, Marlies; Palevsky, Paul M.; Qiu, Haibo; Pettilä, Ville; Schneider, Antoine G.; Smith, Orla M.; Vaara, Suvi T.; Weir, Matthew; Dreyfuss, Didier; Bagshaw, Sean M.; null, null; Gaudry, Stéphane; Eastwood, Glenn M.; Peck, Leah; Young, Helen; Kruger, Peter; Laurie, Gordon; Saylor, Emma; Meyer, Jason; Venz, Ellen; Wetzig, Krista; French, Craig; McGain, Forbes; Mulder, John; Fennessy, Gerard; Koottayi, Sathyajith; Bates, Samantha; Towns, Miriam; Morgan, Rebecca; Tippett, Anna; Udy, Andrew; Mason, Chris; Licari, Elisa; Gantner, Dashiell; McClure, Jason; Nichol, Alistair; McCracken, Phoebe; Board, Jasmin; Martin, Emma; Vallance, Shirley; Young, Meredith; Vladic, Chelsey; McGloughlin, Steve; Gattas, David; Buhr, Heidi; Coles, Jennifer; Hutch, Debra; Wun, James; Cole, Louise; Whitehead, Christina; Lowrey, Julie; Masters, Kristy; Gresham, Rebecca; Campbell, Victoria; Gutierrez, David; Brailsford, Jane; Forbes, Loretta; Murray, Lauren; Maguire, Teena; NiChonghaile, Martina; Orford, Neil; Bone, Allison; Elderkin, Tania; Salerno, Tania; Chimunda, Tim; Fletcher, Jason; Broadfield, Emma; Porwal, Sanjay; Knott, Cameron; Boschert, Catherine; Smith, Julie; Richardson, Angus; Hill, Dianne; Duke, Graeme; Oziemski, Peter; Cegarra, Santiago; Chan, Peter; Welsh, Deborah; Hunter, Stephanie; Roodenburg, Owen; Dyett, John; Kokotsis, Nicos; Moser, Max; Yang, null; Padayachee, Laven; Vetro, Joseph; Gangopadhyay, Himangsu; Kaufman, Melissa; Ghosh, Angaj; Said, Simone; Patel, Alpesh; Bihari, Shailesh; Matheson, Elisha; Jin, Xia; Shrestha, Tapaswi; Schwartz, Kate; Cross, Rosalba; Cheung, Winston; Wong, Helen; Kol, Mark; Shah, Asim; Wang, Amanda Y.; Endre, Zoltan; Bradford, Celia; Janin, Pierre; Finfer, Simon; Diel, Naomi; Gatward, Jonathan; Hammond, Naomi; Delaney, Anthony; Bass, Frances; Yarad, Elizabeth; Buscher, Hergen; Reynolds, Claire; Baker, Nerilee; Bellmann, Romuald; Peer, Andreas; Hasslacher, Julia; Koglberger, Paul; Klein, Sebastian; Zotter, Klemens; Brandtner, Anna; Finkenstedt, Armin; Ditlbacher, Adelheid; Hartig, Frank; Fries, Dietmar; Bachler, Mirjam; Schenk, Bettina; Wagner, Martin; Eller, Philipp; Staudinger, Thomas; Tiller, Esther; Schellongowski, Peter; Bojic, Andja; Bracke, Stephanie; De Crop, Luc; Vermeiren, Daisy; Thome, Fernando; Chiella, Bianca; Fendt, Lucia; Antunes, Veronica; Lafrance, Jean-Philippe; D'Aragon, Frédérick; St-Arnaud, Charles; Mayette, Michael; Carbonnaeu, Élaine; Marchand, Joannie; Masse, Marie-Hélène; Ladouceur, Marilène; Turgeon, Alexis F.; Lauzier, François; Bellemare, David; Francoeur, Charles Langis; LeBlanc, Guillaume; Guilbault, Gabrielle; Grenier, Stéphanie; Cloutier, Eve; Boivin, Annick; Delisle-Thibault, Charles; Giannakouros, Panagiota; Costerousse, Olivier; Cailhier, Jean-François; Carrier, François-Martin; Ghamraoui, Ali; Lebrasseur, Martine; Benettaib, Fatna; Salamé, Maya; Boumahni, Dounia; Sia, Ying Tung; Naud, Jean-François; Roy, Isabelle; Stelfox, Henry T.; Ruddell, Stacey; Manns, Braden J.; Duggan, Shelley; Carney, Dominic; Barchard, Jennifer; Whitlock, Richard P.; Belley-Cote, Emilie; Savija, Nevena; Sabev, Alexandra; Campbell, Troy; Creary, Thais; Devereaux, Kelson; Brodutch, Shira; Rigatto, Claudio; Paunovic, Bojan; Mooney, Owen; Glybina, Anna; Harasemiw, Oksana; Di Nella, Michelle; Harmon, John; Mehta, Navdeep; Lakatos, Louis; Haslam, Nicole; Lellouche, Francois; Simon, Mathieu; Tung, Ying; Lizotte, Patricia; Bourchard, Pierre-Alexandre; Rochwerg, Bram; Karachi, Tim; Millen, Tina; Muscedere, John; Maslove, David; Boyd, J. Gordon; Sibley, Stephanie; Drover, John; Hunt, Miranda; Georgescu, Ilinca; Wax, Randy; Lenga, Ilan; Sridhar, Kavita; Steele, Andrew; Fusco, Kelly; Ghate, Taneera; Tolibas, Michael; Robinson, Holly; Weir, Matthew A.; Taneja, Ravi; Ball, Ian M.; Garg, Amit; Campbell, Eileen; Ovsenek, Athena; van Diepen, Sean; Baig, Nadia; Magder, Sheldon; Yao, Han; Alam, Ahsan; Campisi, Josie; MacIntyre, Erika; Rokosh, Ella; Scherr, Kimberly; Lapinsky, Stephen; Mehta, Sangeeta; Shah, Sumesh; Niven, Daniel J.; Russell, Michael; Jim, Kym; Brown, Gillian; Oxtoby, Kerry; Hall, Adam; Benoit, Luc; Sokolowski, Colleen; Prasad, Bhanu; Rao, Jag; Giebel, Shelley; Kutsogiannis, Demetrios J.; Thompson, Patricia; Thompson, Tayne; Cirone, Robert; Kavikondala, Kanthi; Soth, Mark; Clarke, France; Takaoka, Alyson; Mazer, David; Burns, Karen; Friedrich, Jan; Klein, David; Sandhu, Gyan; Santos, Marlene; Khalid, Imrana; Hodder, Jennifer; Dodek, Peter; Ayas, Najib; Alcuaz, Victoria; Suen, Gabriel; Rewa, Oleksa; Singh, Gurmeet; Norris, Sean; Gibson, Neil; Arias, Castro; Shami, Aysha; Pelletier, Celine; Zahirieh, Alireza; Amaral, Andre; Marinoff, Nicole; Kaur, Navjot; Perez, Adic; Wang, Jane; Haljan, Gregory; Condin, Christopher; McIntyre, Lauralyn; Gomes, Brigette; Porteous, Rebecca; Watpool, Irene; Hiremath, Swapnil; Clark, Edward; Herridge, Margaret S.; Backhouse, Felicity; Wilcox, M. Elizabeth; Walczak, Karolina; Ki, Vincent; Sharman, Asheer; Romano, Martin; Gibney, R. T. Noel; Romanovsky, Adam S.; McCoshen, Lorena; Wood, Gordon; Ovakim, Daniel; Auld, Fiona; Carney, Gayle; Duan, Meili; Ji, Xiaojun; Guo, Dongchen; Qi, Zhili; Lin, Jin; Zhang, Meng; Dong, Lei; Liu, Jingfeng; Liu, Pei; Zhi, Deyuan; Bai, Guoqiang; Qiu, Yu; Yang, Ziqi; Bai, Jing; Liu, Zhuang; Zhuang, Haizhou; Wang, Haiman; Li, Jian; Zhao, Mengya; Zhou, Xiao; Shi, Xianqing; Ye, Baning; Liu, Manli; Wu, Jing; Fu, Yongjian; Long, Dali; Pan, Yu; Wang, Jinlong; Mei, Huaxian; Zhang, Songsong; Wen, Mingxiang; Yang, Enyu; Mu, Sijie; Li, Jianquan; Hu, Tingting; Qin, Bingyu; Li, Min; Wang, Cunzhen; Dong, Xin; Wang, Kaiwu; Wang, Haibo; Yang, Jianxu; Wang, Chuanyao; Wang, Dongxin; Li, Nan; Yu, Zhui; Xu, Song; Yao, Lan; Hou, Guo; Liu, Zhou; Lu, Liping; Lian, Yingtao; Wang, Chunting; Zhang, Jichen; Ding, Ruiqi; Qi, Guoqing; Wang, Qizhi; Wang, Peng; Meng, Zhaoli; Chen, Man; Hu, Xiaobo; He, Xiandi; Zhao, Shibing; Hang, Lele; Li, Rui; Qin, Suhui; Lu, Kun; Dun, Shijuan; Liu, Cheng; Zhou, Qi; Chen, Zhenzhen; Mei, Jing; Zhang, Minwei; Xu, Hao; Lin, Jincan; Shi, Qindong; Fu, Lijuan; Zeng, Qinjing; Ma, Hongye; Yan, Jinqi; Gao, Lan; Liu, Hongjuan; Zhang, Lei; Li, Hao; He, Xiaona; Fan, Jingqun; Guo, Litao; Liu, Yu; Wang, Xue; Sun, Jingjing; Liu, Zhongmin; Yang, Juan; Ding, Lili; Sheng, Lulu; Liu, Xingang; Yan, Jie; Wang, Quihui; Wang, Yifeng; Zhao, Dan; Zhao, Shuangping; Hu, Chenghuan; Li, Jing; Deng, Fuxing; Qui, Haibo; Yang, Yi; Mo, Min; Pan, Chun; Wu, Changde; Huang, Yingzi; Huang, Lili; Liu, Airan; Korhonen, Anna-Maija; Törnblom, Sanna; Sutinen, Sari; Pettilä, Leena; Heinonen, Jonna; Lappi, Eliria; Suhonen, Taria; Karlsson, Sari; Hoppu, Sanna; Jalkanen, Ville; Kuitunen, Anne; Levoranta, Markus; Långsjö, Jaakko; Ristimäki, Sanna; Malila, Kaisa; Wootten, Anna; Varila, Simo; Järvisalo, Mikko J; Inkinen, Outi; Kentala, Satu; Leivo, Keijo; Haltia, Paivi; Ricard, Jean-Damien; Messika, Jonathan; Tiagarajah, Abirami; Emery, Malo; Dechanet, Aline; Gernez, Coralie; Roux, Damien; Martin-Lefevre, Laurent; Fiancette, Maud; Vinatier, Isabelle; Lacherade, Jean Claude; Colin, Gwenhaël; Lebert, Christine; Azais, Marie-Ange; Yehia, Aihem; Pouplet, Caroline; Lagarrigue, Matthieu Henry-; Seguin, Amélie; Crosby, Laura; Maizel, Julien; Titeca-Beauport, Dimitri; Combes, Alain; Nieszkowska, Ania; Masi, Paul; Demoule, Alexandre; Mayaux, Julien; Dres, Martin; Morawiec, Elise; Decalvele, Maxens; Demiri, Suela; Faure, Morgane; Marios, Clémence; Mallet, Maxime; Ordon, Marie Amélie; Morizot, Laura; Cantien, Marie; Pousset, François; Poirson, Florent; Cohen, Yves; Argaud, Laurent; Cour, Martin; Bitker, Laurent; Simon, Marie; Hernu, Romain; Baudry, Thomas; De La Salle, Sylvie; Robine, Adrien; Sedillot, Nicholas; Tchenio, Xavier; Bouisse, Camille; Roux, Sylvie; Barbar, Saber Davide; Trusson, Rémi; Tamion, Fabienne; Grangé, Steven; Carpentier, Dorothée; Chevrel, Guillaume; Ensenyat-Martin, Luis; Marque, Sophie; Quenot, Jean-Pierre; Andreu, Pascal; Dargent, Auguste; Large, Audrey; Chudeau, Nicolas; Landais, Mickael; Derrien, Benoit; Callahan, Jean Christophe; Guitton, Christophe; Le Moal, Charlène; Robert, Alain; Asehnoune, Karim; Cinotti, Raphaël; Grillot, Nicolas; Demeure, Dominique; Vinsonneau, Christophe; Rahmani, Imen; Marzouk, Mehdi; Dekeyser, Thibault; Sejourne, Caroline; Verlay, Mélanie; Thevenin, Fabienne; Delecolle, Lucie; Thevenin, Didier; Souweine, Bertrand; Coupez, Elisabeth; Adda, Mireille; Eraldi, Jean-Pierre; Marchalot, Antoine; De Prost, Nicolas; Dessap, Armand Mekontso; Razazi, Keyvan; Meziani, Ferhat; Boisrame-Helms, Julie; Clere-Jehl, Raphael; Delabranche, Xavier; Kummerlen, Christine; Merdji, Hamid; Monnier, Alexandra; Rabouel, Yannick; Rahmani, Hassene; Allam, Hayat; Chenaf, Samir; Franja, Vincenta; Pons, Bertrand; Carles, Michel; Martino, Frédéric; Richard, Régine; Zuber, Benjamin; Lacave, Guillaume; Lakhal, Karim; Rozec, Bertrand; Van, Hoa Dang; Boulet, Éric; Fadel, Fouad; Cleophax, Cedric; Dufour, Nicolas; Grant, Caroline; Thuong, Marie; Reignier, Jean; Canet, Emmanuel; Nicolet, Laurent; Boulain, Thierry; Nay, Mai-Anh; Benzekri, Dalila; Barbier, François; Bretagnol, Anne; Kamel, Toufik; Mathonnet, Armelle; Muller, Grégoire; Skarzynski, Marie; Rossi, Julie; Pradet, Amandine; Dos Santos, Sandra; Guery, Aurore; Muller, Lucie; Felix, Luis; Bohé, Julien; Thiéry, Guillaume; Aissaoui, Nadia; Vimpere, Damien; Commeureuc, Morgane; Diehl, Jean-Luc; Guerot, Emmanuel; Liangos, Orfeas; Wittig, Monika; Zarbock, Alexander; Küllmar, Mira; van Waegeningh, Thomas; Rosenow, Nadine; Brickell, Kathy; Doran, Peter; Murray, Patrick T.; Landoni, Giovanni; Lembo, Rosalba; Zangrillo, Alberto; Monti, Giacomo; Tozzi, Margherita; Marzaroli, Matteo; Lombardi, Gaetano; Paternoster, Gianluca; Vitiello, Michelangelo; McGuinness, Shay; Parke, Rachael; Butler, Magdalena; Gilder, Eileen; Cowdrey, Keri-Anne; Wallace, Samantha; Hallion, Jane; Woolett, Melissa; Neal, Philippa; Duffy, Karina; Long, Stephanie; McArthur, Colin; Simmonds, Catherine; Chen, Yan; McConnochie, Rachael; Newby, Lynette; Knight, David; Henderson, Seton; Mehrtens, Jan; Morgan, Stacey; Morris, Anna; Vander Hayden, Kymbalee; Burke, Tara; Bailey, Matthew; Freebairn, Ross; Chadwick, Lesley; Park, Penelope; Rolls, Christine; Thomas, Liz; Buehner, Ulrike; Williams, Erin; Albrett, Jonathan; Kirkham, Simon; Jackson, Carolyn; Browne, Troy; Goodson, Jennifer; Jackson, David; Houghton, James; Callender, Owen; Higson, Vicki; Keet, Owen; Dominy, Clive; Young, Paul; Hunt, Anna; Judd, Harriet; Lawrence, Cassie; Olatunji, Shaanti; Robertson, Yvonne; Latimer-Bell, Charlotte; Hendry, Deborah; Mckay-Vucago, Agnes; Beehre, Nina; Eden, null; Lesona, null; Navarra, Leanlove; Robinson, Chelsea; Jang, Ryan; Junge, Andrea; Lambert, Bridget; Thibault, Michel; Eckert, Philippe; Kissling, Sébastien; Polychronopoulos, Erietta; Poli, Elettra; Altarelli, Marco; Schnorf, Madeleine; Mallaird, Samia Abed; Heidegger, Claudia; Perret, Aurelie; Montillier, Philippe; Sangla, Frederic; Neils, Seigenthaller; De Watteville, Aude; Phull, Mandeep-Kaur; George, Aparna; Hussain, Nauman; Pogreban, Tatiana; Lobaz, Steve; Daniels, Alison; Cunningham, Mishell; Kerr, Deborah; Nicholson, Alice; Shanmugasundaram, Pradeep; Abrams, Judith; Manso, Katarina; Hambrook, Geraldine; McKerrow, Elizabeth; Salva, Juvy; Foulkes, Stephen; Wise, Matthew; Morgan, Matt; Brooks, Jenny; Cole, Jade; Davies, Tracy Michelle; Hill, Helen; Thomas, Emma; Vizcaychipi, Marcela; Baharlo, Behrad; Carungcong, Jaime; Costa, Patricia; Martins, Laura; Kapoor, Ritoo; Hazelton, Tracy; Moon, Angela; Musselwhite, Janine; Shelley, Ben; McCall, Philip; Arbane, Gill; Bociek, Aneta; Marotti, Martina; Lim, Rosario; Campos, Sara; Novellas, Neus Grau; Cennamo, Armando; Slack, Andrew; Wyncoll, Duncan; Camporota, Luigi; Sparkes, Simon; Tilley, Rosalinde; Rattray, Austin; Moreland, Gayle; Duffy, Jane; McGonigal, Elizabeth; Hopkins, Philip; Finney, Clare; Smith, John; Noble, Harriet; Watson, Hayley; Harris, Claire-Louise; Clarey, Emma; Corcoran, Eleanor; Beck, James; Howcroft, Clare; Youngs, Nora; Wilby, Elizabeth; Ogg, Bethan; Wolverson, Adam; Lee, Sandra; Butler, Susie; Okubanjo, Maryanne; Hindle, Julia; Welters, Ingeborg; Williams, Karen; Johnson, Emily; Patrick-Heselton, Julie; Shaw, David; Waugh, Victoria; Stewart, Richard; Mwaura, Esther; Wren, Lynn; Mew, Louise; Sutherland, Sara-Beth; Adderley, Jane; Ruddy, Jim; Harkins, Margaret; Kaye, Callum; Scott, Teresa; Mitchell, Wendy; Anderson, Felicity; Willox, Fiona; Jagannathan, Vijay; Clark, Michele; Purv, Sarah; Sharman, Andrew; Meredith, Megan; Ryan, Lucy; Conner, Louise; Peters, Cecilia; Harvey, Dan; Roshdy, Ashraf; Collins, Amy; Sim, Malcolm; Henderson, Steven; Chee, Nigel; Pitts, Sally; Bowman, Katie; Dilawershah, Maria; Vamplew, Luke; Howe, Elizabeth; Rogers, Paula; Hernandez, Clara; Prendergast, Clara; Benton, Jane; Rosenberg, Alex; Forni, Lui G.; Grant, Alice; Carvelli, Paula; Raithatha, Ajay; Bird, Sarah; Richardson, Max; Needham, Matthew; Hirst, Claire; Ball, Jonathan; Leaver, Susannah; Howlett, Luisa; Delgado, Carlos Castro; Farnell-Ward, Sarah; Farrah, Helen; Gray, Geraldine; Joseph, Gipsy; Robinson, Francesca; Tridente, Ascanio; Harrop, Clare; Shuker, Karen; McLaughlan, Derek; Ramsey, Judith; Meehan, Sharon; Rose, Bernd Oliver; Reece-Anthony, Rosie; Gurung, Babita; Whitehouse, Tony; Snelson, Catherine; Veenith, Tonny; Johnston, Andy; Cooper, Lauren; Carrera, Ron; Ellis, Karen; Fellows, Emma; Harkett, Samanth; Bergin, Colin; Spruce, Elaine; Despy, Liesl; Goundry, Stephanie; Dooley, Natalie; Mason, Tracy; Clark, Amy; Dignam, Gemma; Ward, Geraldine; Attwood, Ben; Parsons, Penny; Mason, Sophie; Margarson, Michael; Lord, Jenny; McGlone, Philip; Hodgson, Luke E.; Chadbourn, Indra; Gomez, Raquel; Margalef, Jordi; Pretorius, Rinus; Hamshere, Alexandra; Carter, Joseph; Cahill, Hazel; Grainger, Lia; Howard, Kate; Forshaw, Greg; Guy, Zoe; Kashani, Kianoush B.; Albright, Robert C.; Amsbaugh, Amy; Stoltenberg, Anita; Niven, Alexander S.; Lynch, Matthew; O'Mara, AnnMarie; Naeem, Syed; Sharif, Sairah; Goulart, Joyce McKenney; Tolwani, Ashita; Lyas, Claretha; Latta, Laura; Bihorac, Azra; Hashemighouchani, Haleh; Efron, Philip; Ruppert, Matthew; Cupka, Julie; Kiley, Sean; Carson, Joshua; White, Peggy; Omalay, George; Brown, Sherry; Velez, Laura; zMarceron, Alina; Neyra, Javier A.; Aycinena, Juan Carlos; Elias, Madona; Ortiz-Soriano, Victor M.; Hauschild, Caroline; Dorfman, Robert
Contributors:	Wald, Ron; Gaudry, Stephane; da Costa, Bruno R.; Adhikari, Neill K. J.; Bellomo, Rinaldo; Du, Bin; Gallagher, Martin P.; Hoste, Eric A.; Lamontagne, Françoi; Joannidis, Michael; Liu, Kathleen D.; Mcauley, Daniel F.; Mcguinness, Shay P.; Nichol, Alistair D.; Ostermann, Marlie; Palevsky, Paul M.; Qiu, Haibo; Pettilä, Ville; Schneider, Antoine G.; Smith, Orla M.; Vaara, Suvi T.; Weir, Matthew; Dreyfuss, Didier; Bagshaw, Sean M.; Null, Null; Gaudry, Stéphane; Eastwood, Glenn M.; Peck, Leah; Young, Helen; Kruger, Peter; Laurie, Gordon; Saylor, Emma; Meyer, Jason; Venz, Ellen; Wetzig, Krista; French, Craig; Mcgain, Forbe; Mulder, John; Fennessy, Gerard; Koottayi, Sathyajith; Bates, Samantha; Towns, Miriam; Morgan, Rebecca; Tippett, Anna; Udy, Andrew; Mason, Chri; Licari, Elisa; Gantner, Dashiell; Mcclure, Jason; Nichol, Alistair; Mccracken, Phoebe; Board, Jasmin; Martin, Emma; Vallance, Shirley; Young, Meredith; Vladic, Chelsey; Mcgloughlin, Steve; Gattas, David; Buhr, Heidi; Coles, Jennifer; Hutch, Debra; Wun, Jame; Cole, Louise; Whitehead, Christina; Lowrey, Julie; Masters, Kristy; Gresham, Rebecca; Campbell, Victoria; Gutierrez, David; Brailsford, Jane; Forbes, Loretta; Murray, Lauren; Maguire, Teena; Nichonghaile, Martina; Orford, Neil; Bone, Allison; Elderkin, Tania
Publication Year:	2023
Collection:	Università degli Studi della Basilicata: CINECA IRIS
Subject Terms:	Acute kidney injury; Continuou; Intermittent hemodialysi; Modality; Mortality; Randomized trial; Renal-replacement therapy
Description:	Background: There is controversy regarding the optimal renal-replacement therapy (RRT) modality for critically ill patients with acute kidney injury (AKI). Methods: We conducted a secondary analysis of the STandard versus Accelerated Renal Replacement Therapy in Acute Kidney Injury (STARRT-AKI) trial to compare outcomes among patients who initiated RRT with either continuous renal replacement therapy (CRRT) or intermittent hemodialysis (IHD). We generated a propensity score for the likelihood of receiving CRRT and used inverse probability of treatment with overlap-weighting to address baseline inter-group differences. The primary outcome was a composite of death or RRT dependence at 90-days after randomization. Results: We identified 1590 trial participants who initially received CRRT and 606 who initially received IHD. The composite outcome of death or RRT dependence at 90-days occurred in 823 (51.8%) patients who commenced CRRT and 329 (54.3%) patients who commenced IHD (unadjusted odds ratio (OR) 0.90; 95% confidence interval (CI) 0.75-1.09). After balancing baseline characteristics with overlap weighting, initial receipt of CRRT was associated with a lower risk of death or RRT dependence at 90-days compared with initial receipt of IHD (OR 0.81; 95% CI 0.66-0.99). This association was predominantly driven by a lower risk of RRT dependence at 90-days (OR 0.61; 95% CI 0.39-0.94). Conclusions: In critically ill patients with severe AKI, initiation of CRRT, as compared to IHD, was associated with a significant reduction in the composite outcome of death or RRT dependence at 90-days.
Document Type:	article in journal/newspaper
Language:	English
Relation:	info:eu-repo/semantics/altIdentifier/wos/WOS:001091209100001; volume:49; issue:11; firstpage:1305; lastpage:1316; numberofpages:12; journal:INTENSIVE CARE MEDICINE; https://hdl.handle.net/11563/190069
DOI:	10.1007/s00134-023-07211-8
Availability:	https://hdl.handle.net/11563/190069; https://doi.org/10.1007/s00134-023-07211-8
Rights:	info:eu-repo/semantics/openAccess
Accession Number:	edsbas.19FFB6FC
Database:	BASE