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Bile acid diarrhea in patients with chronic diarrhea. Current appraisal and recommendations for clinical practice

Title: Bile acid diarrhea in patients with chronic diarrhea. Current appraisal and recommendations for clinical practice
Authors: Barbara G; Bellini M; Portincasa P; Stanghellini V; Annibale B; Benedetti A; Cammarota G; Fries W; Usai Satta P; Corazziari ES
Contributors: Barbara, G; Bellini, M; Portincasa, P; Stanghellini, V; Annibale, B; Benedetti, A; Cammarota, G; Fries, W; Usai Satta, P; Corazziari, Es
Publisher Information: Elsevier Science; New York
Publication Year: 2025
Collection: Sapienza Università di Roma: CINECA IRIS
Subject Terms: bile acid diarrhea; bile acid sequestrant; diagnosi; diarrhea; irritable bowel syndrome; 75sehcat test
Description: Bile Acid Diarrhea (BAD) is a common cause of chronic diarrhea, often accompanied by urgency, occasional fecal incontinence, abdominal pain, and fatigue. A nationwide survey has shown limited awareness of BAD within the Italian medical community, prompting a panel of experts to develop a Position Paper that outlines the most practical and cost-saving diagnostic investigations and treatments for this frequently overlooked condition. The document provides an overview of the epidemiology, pathophysiology, clinical manifestations, and classification of the different types of Bile Acid Diarrhea (BAD). A key focus is the diagnostic approach to identifying and managing the many undiagnosed BAD patients in both primary care and specialized medical settings. Finally, the paper addresses the optimal therapeutic strategies for BAD, including traditional bile acid sequestrants and newer, promising treatments.
Document Type: article in journal/newspaper
Language: English
Relation: info:eu-repo/semantics/altIdentifier/pmid/39827025; info:eu-repo/semantics/altIdentifier/wos/WOS:001434768600001; volume:57; issue:3; firstpage:680; lastpage:687; numberofpages:8; journal:DIGESTIVE AND LIVER DISEASE; https://hdl.handle.net/11573/1731792
DOI: 10.1016/j.dld.2024.12.019
Availability: https://hdl.handle.net/11573/1731792; https://doi.org/10.1016/j.dld.2024.12.019
Rights: info:eu-repo/semantics/openAccess
Accession Number: edsbas.1A1622CD
Database: BASE