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Atypical complications and co-morbidities of type 1 diabetes in young adults

Title: Atypical complications and co-morbidities of type 1 diabetes in young adults
Authors: James, S; Barber, R; Forster, J; Sawatsky, L; Berry, S; James, O; Abel, K; Trigg, C; Donaghue, KC; Craig, ME; Saiyed, M; Salis, SS; Wood, J; Staels, W
Publisher Information: Elsevier BV
Publication Year: 2025
Collection: The University of Melbourne: Digital Repository
Description: AIMS: Our review aimed to determine the prevalence of - and factors associated with - hearing loss, oral and olfactory disease, frozen shoulder, trigger finger, and hair loss in young adults with type 1 diabetes. These conditions were selected based on research team interests, existing literature, and group discussion. METHODS: We conducted a quantitative narrative review using a systematic process to identify cohort and cross-sectional studies involving young adults with type 1 diabetes (mean age 18-30 years). PubMed, CINAHL, and Cochrane were searched (January 2000-February 2024). Grey literature was not restricted, and quality appraisal was undertaken. Extracted data were synthesised and summarised narratively. RESULTS: The initial search found 3924 records and after title, abstract and full-text review, 19 records met inclusion criteria. Hearing loss prevalence ranged from 22.6 to 48.0 %, with age, diabetes duration, and systolic blood pressure identified as prominent associated features. For oral disease, peridontitis prevalence was 4.7 %, while alveolar bone loss ranged from 24.6 to 43.9 %; age was the primary associated factor. No eligible data were identified regarding frozen shoulder, trigger finger, or hair loss. CONCLUSIONS: Further research is needed to characterize the prevalence and risk factors of atypical complications in type 1 diabetes. Clinical care should be guided by a robust understanding of these under-recognised comorbidities.
Document Type: article in journal/newspaper
Language: English
ISSN: 1056-8727
Relation: https://hdl.handle.net/11343/363834
Availability: https://hdl.handle.net/11343/363834
Rights: https://creativecommons.org/licenses/by/4.0 ; CC BY
Accession Number: edsbas.1A9A48C0
Database: BASE