| Title: |
Tunable functional coverage of biocompatible magnesium silicate nanotubes by microwave-assisted silanization |
| Authors: |
Secchi, Valeria; D'Alessio, Daniela; Erroi, Andrea; Mostoni, Silvia; Capitani, Giancarlo; Calloni, Alberto; Bussetti, Gianlorenzo; D'Arienzo, Massimiliano; Lorenzi, Roberto; Keinan-Adamsky, Keren; Rahimipour, Shai; Monguzzi, Angelo; Campione, Marcello |
| Contributors: |
Secchi, V; D'Alessio, D; Erroi, A; Mostoni, S; Capitani, G; Calloni, A; Bussetti, G; D'Arienzo, M; Lorenzi, R; Keinan-Adamsky, K; Rahimipour, S; Monguzzi, A; Campione, M |
| Publisher Information: |
Royal Society of Chemistry; GB |
| Publication Year: |
2025 |
| Collection: |
Università degli Studi di Milano-Bicocca: BOA (Bicocca Open Archive) |
| Subject Terms: |
nanotube; microwave assisted synthesi; silanization; surface characterization |
| Description: |
The controlled synthesis of biocompatible nanomaterials with tailored composition, size, and functionalities has driven the advancement of nanomedicine, enabling the development of innovative diagnostic and therapeutic strategies. A key challenge in this field is the design of nano-objects exhibiting multiple functionalities, each dedicated to a specific diagnostic or therapeutic purpose. Among these, synthetic stoichiometric chrysotile nanotubes stand out as a highly biocompatible class of non-carbon nanotubes, already demonstrating their potential for diverse applications, including fluorescence, magnetism, singlet-oxygen generation, and scintillation. Expanding this functional versatility, we report a finely tunable approach for controlling the surface silanization using 3-aminopropyl-trimethoxysilane. This is achieved via a microwave-assisted synthesis, which enables mild reaction conditions and significantly reduces processing time. A comprehensive multi-technique characterization is employed to elucidate the structural and chemical features of the mineral-silane interface and the underlying reaction mechanism. |
| Document Type: |
article in journal/newspaper |
| File Description: |
STAMPA |
| Language: |
English |
| Relation: |
info:eu-repo/semantics/altIdentifier/pmid/40843488; info:eu-repo/semantics/altIdentifier/wos/WOS:001554766400001; volume:17; issue:35; firstpage:20259; lastpage:20268; numberofpages:10; journal:NANOSCALE; https://hdl.handle.net/10281/565362 |
| DOI: |
10.1039/d5nr02385h |
| Availability: |
https://hdl.handle.net/10281/565362; https://doi.org/10.1039/d5nr02385h |
| Rights: |
info:eu-repo/semantics/openAccess ; license:Creative Commons ; license uri:http://creativecommons.org/licenses/by-nc/4.0/ |
| Accession Number: |
edsbas.1A9B7E2D |
| Database: |
BASE |