| Title: |
Neighborhood Resources Associated With Psychological Trajectories and Neural Reactivity to Reward After Trauma |
| Authors: |
Webb, E Kate; Stevens, Jennifer S; Ely, Timothy D; Lebois, Lauren A M; van Rooij, Sanne J H; Bruce, Steven E; House, Stacey L; Beaudoin, Francesca L; An, Xinming; Neylan, Thomas C; Clifford, Gari D; Linnstaedt, Sarah D; Germine, Laura T; Bollen, Kenneth A; Rauch, Scott L; Haran, John P; Storrow, Alan B; Lewandowski, Christopher; Musey, Paul I; Hendry, Phyllis L; Sheikh, Sophia; Jones, Christopher W; Punches, Brittany E; Swor, Robert A; Murty, Vishnu P; Hudak, Lauren A; Pascual, Jose L; Seamon, Mark J; Datner, Elizabeth M; Pearson, Claire; Peak, David A; Domeier, Robert M; Rathlev, Niels K; O'Neil, Brian J; Sergot, Paulina; Sanchez, Leon D; Joormann, Jutta; Pizzagalli, Diego A; Harte, Steven E; Kessler, Ronald C; Koenen, Karestan C; Ressler, Kerry J; McLean, Samuel A; Harnett, Nathaniel G |
| Contributors: |
Emergency Medicine |
| Source: |
JAMA psychiatry ; United States |
| Publication Year: |
2024 |
| Collection: |
University of Massachusetts, Medical School: eScholarship@UMMS |
| Description: |
Importance: Research on resilience after trauma has often focused on individual-level factors (eg, ability to cope with adversity) and overlooked influential neighborhood-level factors that may help mitigate the development of posttraumatic stress disorder (PTSD). Objective: To investigate whether an interaction between residential greenspace and self-reported individual resources was associated with a resilient PTSD trajectory (ie, low/no symptoms) and to test if the association between greenspace and PTSD trajectory was mediated by neural reactivity to reward. Design, setting, and participants: As part of a longitudinal cohort study, trauma survivors were recruited from emergency departments across the US. Two weeks after trauma, a subset of participants underwent functional magnetic resonance imaging during a monetary reward task. Study data were analyzed from January to November 2023. Exposures: Residential greenspace within a 100-m buffer of each participant's home address was derived from satellite imagery and quantified using the Normalized Difference Vegetation Index and perceived individual resources measured by the Connor-Davidson Resilience Scale (CD-RISC). Main outcome and measures: PTSD symptom severity measured at 2 weeks, 8 weeks, 3 months, and 6 months after trauma. Neural responses to monetary reward in reward-related regions (ie, amygdala, nucleus accumbens, orbitofrontal cortex) was a secondary outcome. Covariates included both geocoded (eg, area deprivation index) and self-reported characteristics (eg, childhood maltreatment, income). Results: In 2597 trauma survivors (mean [SD] age, 36.5 [13.4] years; 1637 female [63%]; 1304 non-Hispanic Black [50.2%], 289 Hispanic [11.1%], 901 non-Hispanic White [34.7%], 93 non-Hispanic other race [3.6%], and 10 missing/unreported [0.4%]), 6 PTSD trajectories (resilient, nonremitting high, nonremitting moderate, slow recovery, rapid recovery, delayed) were identified through latent-class mixed-effect modeling. Multinominal logistic regressions revealed that ... |
| Document Type: |
article in journal/newspaper |
| File Description: |
application/pdf |
| Language: |
English |
| Relation: |
JAMA Psychiatry; https://doi.org/10.1001/jamapsychiatry.2024.2148; Webb EK, Stevens JS, Ely TD, Lebois LAM, van Rooij SJH, Bruce SE, House SL, Beaudoin FL, An X, Neylan TC, Clifford GD, Linnstaedt SD, Germine LT, Bollen KA, Rauch SL, Haran JP, Storrow AB, Lewandowski C, Musey PI Jr, Hendry PL, Sheikh S, Jones CW, Punches BE, Swor RA, Murty VP, Hudak LA, Pascual JL, Seamon MJ, Datner EM, Pearson C, Peak DA, Domeier RM, Rathlev NK, O'Neil BJ, Sergot P, Sanchez LD, Joormann J, Pizzagalli DA, Harte SE, Kessler RC, Koenen KC, Ressler KJ, McLean SA, Harnett NG. Neighborhood Resources Associated With Psychological Trajectories and Neural Reactivity to Reward After Trauma. JAMA Psychiatry. 2024 Jul 31:e242148. doi:10.1001/jamapsychiatry.2024.2148. Epub ahead of print. PMID: 39083325; PMCID: PMC11292566.; http://hdl.handle.net/20.500.14038/53739 |
| DOI: |
10.1001/jamapsychiatry.2024.2148 |
| Availability: |
https://doi.org/10.1001/jamapsychiatry.2024.2148; https://hdl.handle.net/20.500.14038/53739 |
| Rights: |
This is an open access article distributed under the terms of the CC-BY License. © 2024 Webb EK et al. JAMA Psychiatry. ; https://jamanetwork.com/pages/cc-by-license-permissions |
| Accession Number: |
edsbas.1B2E1B03 |
| Database: |
BASE |