Virologic and immunologic outcomes of treatment with integrase inhibitors in a real-world setting: The RESPOND cohort consortium
| Title: | Virologic and immunologic outcomes of treatment with integrase inhibitors in a real-world setting: The RESPOND cohort consortium |
|---|---|
| Authors: | Neesgaard B.; Mocroft A.; Zangerle R.; Wit F.; Lampe F.; Gunthard H. F.; Necsoi C.; Law M.; Mussini C.; Castagna A.; Monforte A. D.; Pradier C.; Chkhartisvilli N.; Reyes-Uruena J.; Vehreschild J. J.; Wasmuth J. -C.; Sonnerborg A.; Stephan C.; Greenberg L.; Llibre J. M.; Volny-Anne A.; Peters L.; Pelchen-Matthews A.; Vannappagari V.; Gallant J.; Rieger A.; Youle M.; Braun D.; de Wit S.; Petoumenos K.; Borghi V.; Spagnuolo V.; Tsertsvadze T.; Lundgren J. |
| Contributors: | Neesgaard, B.; Mocroft, A.; Zangerle, R.; Wit, F.; Lampe, F.; Gunthard, H. F.; Necsoi, C.; Law, M.; Mussini, C.; Castagna, A.; Monforte, A. D.; Pradier, C.; Chkhartisvilli, N.; Reyes-Uruena, J.; Vehreschild, J. J.; Wasmuth, J. -C.; Sonnerborg, A.; Stephan, C.; Greenberg, L.; Llibre, J. M.; Volny-Anne, A.; Peters, L.; Pelchen-Matthews, A.; Vannappagari, V.; Gallant, J.; Rieger, A.; Youle, M.; Braun, D.; De Wit, S.; Petoumenos, K.; Borghi, V.; Spagnuolo, V.; Tsertsvadze, T.; Lundgren, J. |
| Publication Year: | 2020 |
| Collection: | Archivio della ricerca dell'Università di Modena e Reggio Emilia (Unimore: IRIS) |
| Description: | Objectives To compare virologic and immunologic outcomes of integrase inhibitor (INSTI)-containing, contemporary boosted protease inhibitor (PI/b)-containing and non-nucleotide reverse transcriptase inhibitor (NNRTI)-containing regimens in a real-life setting. Methods Using logistic regression, virologic and immunologic outcomes of INSTI use were compared to outcomes of PI/b or NNRTI treatment 12 months after treatment start or switch, for participants in the RESPOND cohort consortium. A composite treatment outcome (cTO) was used, defining success as viral load (VL) |
| Document Type: | article in journal/newspaper |
| Language: | English |
| Relation: | info:eu-repo/semantics/altIdentifier/pmid/33382756; info:eu-repo/semantics/altIdentifier/wos/WOS:000605651900095; volume:15; issue:12; firstpage:e0243625; lastpage:e0243625; journal:PLOS ONE; https://hdl.handle.net/11380/1227338 |
| DOI: | 10.1371/journal.pone.0243625 |
| Availability: | https://hdl.handle.net/11380/1227338; https://doi.org/10.1371/journal.pone.0243625 |
| Rights: | info:eu-repo/semantics/openAccess |
| Accession Number: | edsbas.1C504C62 |
| Database: | BASE |