| Title: |
Effectiveness and safety of two‐drug regimens containing an integrase inhibitor and reverse transcriptase inhibitor in a cohort of virologically suppressed people with HIV : Data from the COMBINE ‐2 study |
| Authors: |
Mussini, Cristina; Henegar, Cassidy; Assoumou, Lambert; de Wit, Stephane; Johnson, Margaret; Quiros‐Roldan, Eugenia; Kenyon, Chris; Deschanvres, Colin; Zucman, David; Post, Frank; Movahedi, Roya; Comi, Laura; Fox, Julie; Liegeon, Geoffrey; Martin, Charlotte; Edwards, Jonathan; Tiecco, Giorgio; Delforge, Marc; Ragone, Leigh; Jones, Bryn; van Wyk, Jean; Aboud, Michael; Fletcher, Carl; Pozniak, Anton; Vannappagari, Vani |
| Contributors: |
Mussini, Cristina; Henegar, Cassidy; Assoumou, Lambert; De Wit, Stephane; Johnson, Margaret; Quiros‐roldan, Eugenia; Kenyon, Chri; Deschanvres, Colin; Zucman, David; Post, Frank; Movahedi, Roya; Comi, Laura; Fox, Julie; Liegeon, Geoffrey; Martin, Charlotte; Edwards, Jonathan; Tiecco, Giorgio; Delforge, Marc; Ragone, Leigh; Jones, Bryn; Van Wyk, Jean; Aboud, Michael; Fletcher, Carl; Pozniak, Anton; Vannappagari, Vani |
| Publication Year: |
2026 |
| Collection: |
Archivio della ricerca dell'Università di Modena e Reggio Emilia (Unimore: IRIS) |
| Subject Terms: |
dolutegravir/lamivudine; dolutegravir/rilpivirine; integrase inhibitor; two‐drug regimens |
| Description: |
Objectives: This study assessed real-world effectiveness and safety of switching to dual therapy regimens consisting of an integrase inhibitor (INSTI), and reverse transcriptase inhibitor (RTI), among suppressed people living with HIV in Europe. Methods: This observational cohort enrolled adults with HIV from 28 sites across Europe who were switching to a two-drug regimen of an INSTI plus a nucleoside reverse transcriptase inhibitor or non-nucleoside reverse transcriptase inhibitor while suppressed [viral load (VL) |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| Relation: |
info:eu-repo/semantics/altIdentifier/pmid/41498461; info:eu-repo/semantics/altIdentifier/wos/WOS:001655582700001; firstpage:1; lastpage:13; journal:HIV MEDICINE; https://hdl.handle.net/11380/1396092 |
| DOI: |
10.1111/hiv.70187 |
| Availability: |
https://hdl.handle.net/11380/1396092; https://doi.org/10.1111/hiv.70187 |
| Rights: |
info:eu-repo/semantics/openAccess ; license:[IR] creative-commons ; license uri:http://creativecommons.org/licenses/by/4.0/ |
| Accession Number: |
edsbas.1C767E |
| Database: |
BASE |