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P-1435. Effectiveness of RSV Immunization among Infants in Their First RSV Season in the United States, 2023-2024 and 2024-2025 Seasons

Title: P-1435. Effectiveness of RSV Immunization among Infants in Their First RSV Season in the United States, 2023-2024 and 2024-2025 Seasons
Authors: Payne, Amanda B; Battan-Wraith, Steph; Reese, Sarah E; Hathaway, Cassandra A; Tartof, Sara Y; Natarajan, Karthik; Irving, Stephanie; Grannis, Shaun J; Chickery, Sean M; Vazquez-Benitez, Gabriela; Dascomb, Kristin K; Salas, S Bianca; Bezi, Cassandra; Sy, Lina S; Lewin, Bruno; Stockwell, Melissa S; Stephens, Ashley B; Han, Jungmi; Naleway, Allison L; Dixon, Brian E; Rogerson, Colin; Duszynski, Thomas; Fadel, William F; Ball, Sarah W; Cao, Jingran; McEvoy, Charlene E; Sheffield, Tamara; Bride, Daniel; Arndorfer, Julie; Van Otterloo, Joshua; Kautz, Amber; Ciesla, Allison Avrich; Najdowski, Morgan; Mak, Josephine; DeCuir, Jennifer; Wiegand, Ryan E; Link-Gelles, Ruth
Source: Open Forum Infectious Diseases ; volume 13, issue Supplement_1 ; ISSN 2328-8957
Publisher Information: Oxford University Press (OUP)
Publication Year: 2026
Description: Background During the 2023-2024 and 2024-2025 respiratory virus seasons, two products, a maternal vaccine (Abrysvo, by Pfizer) and an infant monoclonal antibody (nirsevimab), were recommended in the United States to protect infants against severe respiratory syncytial virus (RSV) disease during their first RSV season. We estimated product effectiveness (PE) against RSV-associated emergency department (ED) encounters and hospitalizations among infants in their first RSV season during these seasons.Table 1.Nirsevimab effectiveness against RSV-associated ED encounters and hospitalization among infants in their first RSV season, VISION, 2023-2024 and 2024-2025 RSV seasonsRSV = respiratory syncytial virus; ED = emergency department; IQR = interquartile range; CI = confidence interval; Ref = reference group; PE = product effectiveness; VISION = Virtual SARS-CoV-2, Influenza, and Other respiratory viruses Network*Encounters included those among infants aged
Document Type: article in journal/newspaper
Language: English
DOI: 10.1093/ofid/ofaf695.1622
Availability: https://doi.org/10.1093/ofid/ofaf695.1622; https://academic.oup.com/ofid/article-pdf/13/Supplement_1/ofaf695.1622/66353317/ofaf695.1622.pdf
Rights: https://creativecommons.org/licenses/by/4.0/
Accession Number: edsbas.1D27929B
Database: BASE