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Placental Growth Factor for the Prediction of Adverse Feto-Maternal Outcome in Patients with Pre-Eclampsia

Title: Placental Growth Factor for the Prediction of Adverse Feto-Maternal Outcome in Patients with Pre-Eclampsia
Authors: Akter, Farzana; Dey, Labony; Tabassum, Tamanna; Sharmin, Dina; Begum, Shahana; Akter, Shahena
Source: Journal of Chittagong Medical College Teachers' Association; Vol. 34 No. 2 (2023); 111-117 ; 2224-7300 ; 1609-1558
Publisher Information: Chittagong Medical College Teachers’ Association
Publication Year: 2025
Collection: Bangladesh Journals Online (BanglaJOL)
Subject Terms: Adverse outcomes; Placental growth factor; Pre-eclampsia
Time: Bangladesh
Description: Background: Placental Growth Factor (PlGF) level is reported to be low in preeclampsia. Recent research suggested that it can be a promising tool for predicting adverse fetomaternal outcomes compared to nonspecific biomarkers. This study evaluated the predictive accuracy of maternal serum PlGF level for adverse fetomaternal outcomes in pre-eclamptic women. Materials and methods: Seventy women with preeclampsia from the Department of Obstetrics and Gynecology of Chittagong Medical College Hospital from January 2021 to December 2021. PIGF level at admission was measured by ELISA method, and value >100 and £100 pg/ml was defined as normal and low, respectively. Patients were prospectively followed till delivery to observe fetomaternal outcomes. Results: Out of 70 women, 28 (40%) developed adverse fetomaternal outcomes. The median level of PlGF was significantly lower among women with adverse fetomaternal outcomes than their counterparts [37.0 (18.9 - 61.5) pg/ml versus 122.7 (91.3-156.3) pg/ml, p
Document Type: article in journal/newspaper
File Description: application/pdf
Language: English
Relation: https://banglajol.info/index.php/JCMCTA/article/view/83605/54705; https://banglajol.info/index.php/JCMCTA/article/view/83605
Availability: https://banglajol.info/index.php/JCMCTA/article/view/83605
Rights: Copyright (c) 2023 Journal of Chittagong Medical College Teachers' Association
Accession Number: edsbas.1E3263F6
Database: BASE