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Effect of Acute Intracranial Stenting in Patients With Successful Reperfusion Following Large-Vessel Occlusion Secondary to Intracranial Atherosclerosis: Secondary Analyses of the RESCUE-ICAS Study

Title: Effect of Acute Intracranial Stenting in Patients With Successful Reperfusion Following Large-Vessel Occlusion Secondary to Intracranial Atherosclerosis: Secondary Analyses of the RESCUE-ICAS Study
Authors: Nguyen, Sarah; de Havenon, Adam; Almallouhi, Eyad; Jumaa, Mohammad A.; Inoa, Violiza; Capasso, Francesco; Nahhas, Michael I.; Starke, Robert M.; Fragata, Isabel; Bender, Matthew T.; Moldovan, Krisztina; Yaghi, Shadi; Maier, IlkoL.; Grossberg, Jonathan A.; Jabbour, Pascal M.; Psychogios, Marios-Nikos; Samaniego, Edgar A.; Burkhardt, Jan-Karl; Jankowitz, Brian T.; Abdalkader, Mohamad; Grandhi, Ramesh
Contributors: Nguyen, Sarah; de Havenon, Adam; Almallouhi, Eyad; Jumaa, Mohammad A.; Inoa, Violiza; Capasso, Francesco; Nahhas, Michael I.; Starke, Robert M.; Fragata, Isabel; Bender, Matthew T.; Moldovan, Krisztina; Yaghi, Shadi; Maier, IlkoL.; Grossberg, Jonathan A.; Jabbour, Pascal M.; Psychogios, Marios-Nikos; Samaniego, Edgar A.; Burkhardt, Jan-Karl; Jankowitz, Brian T.; Abdalkader, Mohamad; Grandhi, Ramesh
Publication Year: 2026
Collection: Georg-August-Universität Göttingen: GoeScholar
Description: BACKGROUND: The RESCUE-ICAS study (Registry of Emergent Large-Vessel Occlusion due to Intracranial Stenosis) demonstrated that patients undergoing acute stenting of intracranial atherosclerosis with large-vessel occlusion after mechanical thrombectomy had better outcomes than those undergoing mechanical thrombectomy alone. We present 2 secondary analyses of RESCUE-ICAS to evaluate intracranial stenting among patients who achieved successful reperfusion. METHODS: From a prospective observational cohort of 25 stroke centers (2022–2023), patients with acute intracranial occlusion, National Institutes of Health Stroke Scale score ≥6, and 50% to 99% residual stenosis or occlusion after endovascular thrombectomy were included. In the first analysis, we compared patients with stenting versus those without stenting from among those patients with a final modified Thrombolysis in Cerebral Infarction score of 2B–3. In the second analysis, we compared patients who underwent stenting with those who did not from among the patients with a Thrombolysis in Cerebral Infarction (TICI) score of 2B–3 before stenting. The odds of a favorable 90-day mRS (0–2) and 24-hour MRI infarct volume
Document Type: article in journal/newspaper
Language: English
DOI: 10.1161/SVIN.125.001841
Availability: https://resolver.sub.uni-goettingen.de/purl?gro-2/164458; https://doi.org/10.1161/SVIN.125.001841
Rights: info:eu-repo/semantics/openAccess ; http://creativecommons.org/licenses/by-nc/4.0/
Accession Number: edsbas.205560D9
Database: BASE