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Improved outcomes with oral tongue squamous cell carcinoma in Finland

Title: Improved outcomes with oral tongue squamous cell carcinoma in Finland
Authors: Mroueh, R. (Rayan); Haapaniemi, A. (Aaro); Grénman, R. (Reidar); Laranne, J. (Jussi); Pukkila, M. (Matti); Almangush, A. (Alhadi); Salo, T. (Tuula); Mäkitie, A. (Antti)
Publisher Information: John Wiley & Sons
Publication Year: 2017
Collection: Jultika - University of Oulu repository / Oulun yliopiston julkaisuarkisto
Description: Background: Incidence rates for oral tongue squamous cell carcinoma (SCC) are steadily rising worldwide. Methods: All patients diagnosed with primary oral tongue SCC at the 5 university hospitals in Finland from 2005 to 2009 were studied. The mean follow-up time was 43 months (median, 54 months; range, 0–111 months). Results: Three hundred sixty patients with primary oral tongue SCC were identified. Treatment with curative intent was provided for 328 patients (91%). The 5-year disease-specific survival (DSS) rates were as follows: stage I 87%; stage II 73%; stage III 69%; and stage IV 51%. The 5-year recurrence-free survival in general has improved from 47% in our previous published series (1995–1999) to 65% in the current series (p < .001). Conclusions: The outcome of oral tongue SCC has significantly improved in Finland. However, the relatively high number of disease recurrences in patients with stage I and II disease, when compared with patients with stage III and IV disease, calls for an investigation of new treatment approaches.
Document Type: article in journal/newspaper
File Description: application/pdf
Language: English
ISSN: 1043-3074; 1097-0347
Relation: info:eu-repo/semantics/altIdentifier/pissn/1043-3074; info:eu-repo/semantics/altIdentifier/eissn/1097-0347
Availability: http://urn.fi/urn:nbn:fi-fe2017120855517
Rights: info:eu-repo/semantics/openAccess ; © 2017 Wiley Periodicals, Inc. This is the peer reviewed version of the following article: Mroueh, R., Haapaniemi, A., Grénman, R., Laranne, J., Pukkila, M., Almangush, A., Salo, T. and Mäkitie, A. (2017), Improved outcomes with oral tongue squamous cell carcinoma in Finland. Head Neck, 39: 1306–1312. doi:10.1002/hed.24744, which has been published in final form at https://doi.org/10.1002/hed.24744. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving.
Accession Number: edsbas.20BF9B18
Database: BASE