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Optimizing outcomes in heart transplantation: multidisciplinary Heart Teams and mechanical circulatory support for primary graft dysfunction

Title: Optimizing outcomes in heart transplantation: multidisciplinary Heart Teams and mechanical circulatory support for primary graft dysfunction
Authors: Haneya, Assad; Lanmüller, Pia; Panholzer, Bernd; Sommer, Wiebke; Kuliczkowski, Wiktor; Sokolski, Mateusz; Przybylski, Roman; Schmack, Bastian; Ali-Hasan-Al-Saegh, Sadeq; Takemoto, Sho; Zayat, Rachad; Werner, Nikos
Contributors: Abiomed Europe GmbH
Source: European Heart Journal Supplements ; volume 27, issue Supplement_4, page iv55-iv61 ; ISSN 1520-765X 1554-2815
Publisher Information: Oxford University Press (OUP)
Publication Year: 2025
Description: Heart transplantation (HTx) is a definitive treatment for selected patients with advanced heart failure. However, primary graft dysfunction (PGD), a severe early complication, is a major cause of post-HTx morbidity and mortality. This paper explores the pathophysiology, diagnostic approaches, and management strategies for PGD, with a particular focus on temporary mechanical circulatory support (MCS) devices such as venoarterial extracorporeal membrane oxygenation and Impella. It also highlights the essential role of the multidisciplinary Heart Team in optimizing outcomes through patient-tailored MCS selection and timely intervention.
Document Type: article in journal/newspaper
Language: English
DOI: 10.1093/eurheartjsupp/suaf003
Availability: https://doi.org/10.1093/eurheartjsupp/suaf003; https://academic.oup.com/eurheartjsupp/article-pdf/27/Supplement_4/iv55/63021439/suaf003.pdf
Rights: https://creativecommons.org/licenses/by-nc/4.0/
Accession Number: edsbas.20D490E9
Database: BASE