| Title: |
Shaping development with ESCRTs |
| Authors: |
T. E. Rusten; H. Stenmark; T. Vaccari |
| Contributors: |
T.E. Rusten; T. Vaccari; H. Stenmark |
| Publisher Information: |
Nature |
| Publication Year: |
2012 |
| Collection: |
The University of Milan: Archivio Istituzionale della Ricerca (AIR) |
| Subject Terms: |
Animal; Endosomal Sorting Complexes Required for Transport; Human; Multivesicular Bodie; Protein Transport; Cell Biology; Settore BIO/13 - Biologia Applicata |
| Description: |
Originally identified for their involvement in endosomal sorting and multivesicular endosome (MVE) biogenesis, components of the endosomal sorting complex required for transport (ESCRT) are now known to control additional cellular functions such as receptor signalling, cytokinesis, autophagy, polarity, migration, miRNA activity and mRNA transport. The diverse cell biological functions of ESCRT proteins are translated into a pleiotropic set of developmental trajectories that reflect the wide repertoire of these evolutionarily conserved proteins. |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| Relation: |
info:eu-repo/semantics/altIdentifier/pmid/22193162; info:eu-repo/semantics/altIdentifier/wos/WOS:000298421100007; volume:14; issue:1; firstpage:38; lastpage:45; numberofpages:8; journal:NATURE CELL BIOLOGY; https://hdl.handle.net/2434/491549 |
| DOI: |
10.1038/ncb2381 |
| Availability: |
https://hdl.handle.net/2434/491549; https://doi.org/10.1038/ncb2381 |
| Rights: |
info:eu-repo/semantics/closedAccess |
| Accession Number: |
edsbas.20F45D35 |
| Database: |
BASE |