| Title: |
Production of BRO β-Lactamases and Resistance to Complement in European Moraxella catarrhalis Isolates |
| Authors: |
Schmitz, Franz-Josef; Beeck, Andreas; Perdikouli, Mirella; Boos, Mechthild; Mayer, Susanne; Scheuring, Sybille; Köhrer, Karl; Verhoef, Jan; Fluit, Ad C. |
| Source: |
Journal of Clinical Microbiology ; volume 40, issue 4, page 1546-1548 ; ISSN 0095-1137 1098-660X |
| Publisher Information: |
American Society for Microbiology |
| Publication Year: |
2002 |
| Description: |
Of the 419 Moraxella catarrhalis isolates collected during the 1997-1999 European SENTRY surveillance study, 385 (92%) were β-lactamase positive. Twenty-two (5.7%) produced BRO-2 β-lactamase. Twenty-one new mutations were found in the putative promoter region of the bro genes. Nineteen percent of all isolates tested were complement sensitive. Resistance to β-lactams is not linked to the phylogenetic lineages associated with susceptibility to complement. |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| DOI: |
10.1128/jcm.40.4.1546-1548.2002 |
| DOI: |
10.1128/JCM.40.4.1546-1548.2002 |
| Availability: |
https://doi.org/10.1128/jcm.40.4.1546-1548.2002; https://journals.asm.org/doi/pdf/10.1128/JCM.40.4.1546-1548.2002 |
| Rights: |
https://journals.asm.org/non-commercial-tdm-license |
| Accession Number: |
edsbas.215B8F8F |
| Database: |
BASE |