| Title: |
Prognostic value of aerobic capacity and exercise oxygen pulse in postaortic dissection patients |
| Authors: |
Delsart, Pascal; Delahaye, Camille; Devos, Patrick; Domanski, Olivia; Azzaoui, Richard; Sobocinski, Jonathan; Juthier, Francis; Vincentelli, Andre; Rousse, Natacha; Mugnier, Agnes; Soquet, Jerome; Loobuyck, Valentin; Koussa, Mohamed; Modine, Thomas; Jegou, Bruno; Bical, Antoine; Hysi, Ilir; Fabre, Olivier; Pontana, Francois; Matran, Regis; Mounier-Vehier, Claire; Montaigne, David |
| Contributors: |
CHU Lille; Inserm; Institut Pasteur de Lille; Université de Lille; METRICS : Evaluation des technologies de santé et des pratiques médicales - ULR 2694; Advanced Drug Delivery Systems (ADDS) - U1008; Récepteurs nucléaires, Maladies Cardiovasculaires et Diabète (RNMCD) - U1011; Institut Coeur Poumon CHU Lille; Lille Neurosciences & Cognition (LilNCog) - U 1172; IMPact de l'Environnement Chimique sur la Santé humaine (IMPECS) - ULR 4483; Evaluation des technologies de santé et des pratiques médicales - ULR 2694 METRICS; Récepteurs nucléaires, Maladies Cardiovasculaires et Diabète (EGID) - U1011; Médicaments et biomatériaux à libération contrôlée: mécanismes et optimisation - Advanced Drug Delivery Systems - U 1008 MBLC - ADDS; Récepteurs nucléaires, maladies cardiovasculaires et diabète - U 1011 RNMCD; Récepteurs Nucléaires, Maladies Métaboliques et Cardiovasculaires - U 1011 RNMCD; Centre Hospitalier de Lens; Impact de l'environnement chimique sur la santé humaine - ULR 4483 IMPECS |
| Publication Year: |
2022 |
| Collection: |
LillOA (Lille Open Archive - Université de Lille) |
| Subject Terms: |
prognosis; cardiopulmonary exercise testing; aortic dissection |
| Description: |
BACKGROUND: Although recommendations encourage daily moderate activities in post aortic dissection, very little data exists regarding cardiopulmonary exercise testing (CPET) to personalize those patient's physical rehabilitation and assess their cardiovascular prognosis. METHODS: We aimed at testing the prognostic insight of CPET regarding aortic and cardiovascular events by exploring a prospective cohort of patients followed-up after acute aortic dissection. METHODS: Patients referred to our department after an acute (type A or B) aortic dissection were prospectively included in a cohort between September 2012 and October 2017. CPET was performed once optimal blood pressure control was obtained. Clinical follow-up was done after CPET for new aortic event and major cardio-vascular events (MCE) not directly related to the aorta. RESULTS: Among the 165 patients who underwent CPET, no adverse event was observed during exercise testing. Peak oxygen pulse was 1.46(1.22-1.84) mlO2/beat, that is, 97 (83-113) % of its predicted value, suggesting cardiac exercise limitation in a population under beta blockers (92% of the population). During a follow-up of 39(20-51) months from CPET, 42 aortic event recurrences and 22 MCE not related to aorta occurred. Low peak oxygen pulse ( |
| Document Type: |
article in journal/newspaper |
| File Description: |
application/octet-stream; application/rdf+xml; charset=utf-8 |
| Language: |
English |
| Relation: |
Clinical Cardiology; Clin Cardiol; http://hdl.handle.net/20.500.12210/59765 |
| Availability: |
https://hdl.handle.net/20.500.12210/59765 |
| Rights: |
Attribution 3.0 United States ; info:eu-repo/semantics/openAccess |
| Accession Number: |
edsbas.2173D6B6 |
| Database: |
BASE |