| Title: |
Improving anticoagulation in sub‐Saharan Africa: What are the challenges and how can we overcome them? |
| Authors: |
Mouton, Johannes P.; Blockman, Marc; Sekaggya‐Wiltshire, Christine; Semakula, Jerome; Waitt, Catriona; Pirmohamed, Munir; Cohen, Karen |
| Contributors: |
National Institute for Health Research |
| Source: |
British Journal of Clinical Pharmacology ; volume 87, issue 8, page 3056-3068 ; ISSN 0306-5251 1365-2125 |
| Publisher Information: |
Wiley |
| Publication Year: |
2021 |
| Collection: |
Wiley Online Library (Open Access Articles via Crossref) |
| Description: |
Patients in sub‐Saharan Africa generally have poor anticoagulation control. We review the potential reasons for this poor control, as well as the potential solutions. Challenges include the affordability and centralisation of anticoagulation care, problems with access to medicines and international normalised ratio monitoring, the lack of locally validated standardized dosing protocols, and low levels of anticoagulation knowledge among healthcare workers and patients. Increasing numbers of patients will need anticoagulation in the future because of the increasing burden of noncommunicable disease in the region. We propose that locally developed “warfarin care bundles” which address multiple anticoagulation challenges in combination may be the most appropriate solution in this setting currently. |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| DOI: |
10.1111/bcp.14768 |
| Availability: |
https://doi.org/10.1111/bcp.14768; https://onlinelibrary.wiley.com/doi/pdf/10.1111/bcp.14768; https://onlinelibrary.wiley.com/doi/full-xml/10.1111/bcp.14768; https://bpspubs.onlinelibrary.wiley.com/doi/pdf/10.1111/bcp.14768 |
| Rights: |
http://creativecommons.org/licenses/by/4.0/ |
| Accession Number: |
edsbas.229BC047 |
| Database: |
BASE |