| Title: |
Allocation of authorship and patient enrollment among global clinical trials in oncology. |
| Authors: |
Rubagumya, Fidel; Fundytus, Adam; Keith-Brown, Sophie; Hopman, Wilma M; Gyawali, Bishal; Mukherji, Deborah; Hammad, Nazik; Pramesh, CS; Aggarwal, Ajay; Eniu, Alexandru; Sengar, Manju; Riechelmann, Rachel SR; Sullivan, Richard; Booth, Christopher M |
| Publisher Information: |
Wiley |
| Publication Year: |
2023 |
| Collection: |
London School of Hygiene & Tropical Medicine: LSHTM Research Online |
| Description: |
BACKGROUND: Oncology randomized controlled trials (RCTs) are increasingly global in scope. Whether authorship is equitably shared between investigators from high-income countries (HIC) and low-middle/upper-middle incomes countries (LMIC/UMIC) is not well described. The authors conducted this study to understand the allocation of authorship and patient enrollment across all oncology RCTs conducted globally. METHODS: A cross-sectional retrospective cohort study of phase 3 RCTs (published 2014-2017) that were led by investigators in HIC and recruited patients in LMIC/UMIC. FINDINGS: During 2014-2017, 694 oncology RCTs were published; 636 (92%) were led by investigators from HIC. Among these HIC-led trials, 186 (29%) enrolled patients in LMIC/UMIC. One-third (33%, 62 of 186) of RCTs had no authors from LMIC/UMIC. Forty percent (74 of 186) of RCTs reported patient enrollment by country; in 50% (37 of 74) of these trials, LMIC/UMIC contributed |
| Document Type: |
article in journal/newspaper |
| File Description: |
text |
| Language: |
English |
| ISSN: |
0008-543X |
| Relation: |
https://researchonline.lshtm.ac.uk/id/eprint/4670615/1/Rubagumya-etal-2023-Allocation-of-authorship-and-patient.pdf; Rubagumya, FidelORCID logo; Fundytus, Adam; Keith-Brown, Sophie; Hopman, Wilma M; Gyawali, Bishal; Mukherji, Deborah; Hammad, Nazik; Pramesh, CS; Aggarwal, Ajay ORCID logo; Eniu, AlexandruORCID logo; +4 more.Sengar, Manju; Riechelmann, Rachel SR; Sullivan, Richard; and Booth, Christopher MORCID logo (2023) Allocation of authorship and patient enrollment among global clinical trials in oncology. Cancer, 129 (18). pp. 2856-2863. ISSN 0008-543X DOI:10.1002/cncr.34919 |
| DOI: |
10.1002/cncr.34919 |
| Availability: |
https://researchonline.lshtm.ac.uk/id/eprint/4670615/; https://doi.org/10.1002/cncr.34919 |
| Rights: |
cc_by_nc_4 |
| Accession Number: |
edsbas.24310AC8 |
| Database: |
BASE |